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Diagnosis of Rare Bone Infection Caused by Nocardia by 16S rRNA Gene Sequencing

 

Authors Li S, Shi Y, Xiong Y, Liu Y

Received 5 October 2022

Accepted for publication 30 December 2022

Published 20 January 2023 Volume 2023:16 Pages 347—353

DOI https://doi.org/10.2147/IDR.S392342

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Héctor M. Mora-Montes

Abstract: Nocardia is an aerobic actinomycete that causes serious opportunistic infections in immunocompromised individuals. Gene sequencing is the gold standard for pathogenic bacteria diagnosis. This study uses 16S rRNA gene sequencing to diagnose three cases of bone infections caused by Nocardia , including one rare case (N. cyriacigeorgica), and the clinial features, etiological characteristics, treatment, and prognosis of the patients.
Keywords: Nocardia , 16S rRNA gene sequencing, bone infection, clinical features