已发表论文

社区获得性肺脓肿可归因于牙源性菌群

 

Authors Guo W, Gao B, Li L, Gai W, Yang J, Zhang Y, Wang L

Received 10 June 2019

Accepted for publication 16 July 2019

Published 8 August 2019 Volume 2019:12 Pages 2467—2470

DOI https://doi.org/10.2147/IDR.S218921

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony

Abstract: A lung abscess is an infectious pulmonary disease characterized by pus-filled cavity formation and often an air-fluid level. In this article, we described an indolent community-acquired lung abscess suspected as a tumor previously. A 56-year-old male presented with cough and expectoration for 2 months and hemoptysis for 2 weeks. His physical examinations, whole blood count and C-reactive protein level were normal. The chest computed tomography (CT) scan showed a 40×38×39 mm high-density mass in the right upper pulmonary lobe, with irregular borders. The pathology of a CT-guided percutaneous needle aspiration biopsy showed numerous inflammatory cells and bacteria infiltration without tumor lesions. Bacteriological detection of lung tissue revealed the cause was odontogenic flora. A next-generation sequencing demonstrated the etiologic correlation between lung abscess and periodontitis. After a 2-month pathogen-directed oral antibiotics therapy combined with chlorhexidine gargle oral care, this patient showed a remarkable improvement. Periodontitis can be a cause of a lung abscess, which would be taken into account in the treatment regimes preventing infectious recurrence.
Keywords: community-acquired lung abscess, periodontitis, odontogenic flora




Figure 2 Pathology findings with inflammatory cells infiltration (A) and