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胰腺混合腺泡内分泌癌： 病例报告和简要的文献回顾

 

Authors Liu Z, Dong C, Wang C, Liu Q, Sun D, Wang L

Published Date July 2015 Volume 2015:8 Pages 1633—1642

DOI http://dx.doi.org/10.2147/OTT.S87406

Received 27 April 2015, Accepted 20 May 2015, Published 3 July 2015

Peer reviewers approved by Dr Dekuang Zhao

Approved for publication by Professor Daniele Santini

Abstract: Mixed acinar-endocrine carcinoma (MAEC) of the pancreas is a rare entity. We present a 65-year-old Chinese female who was admitted with jaundice and nagging epigastric pain with intermittent diarrhea for 1 month. She eventually underwent abdominal magnetic resonance imaging, which showed an 8×6 cm mass in the head of the pancreas and showed two abnormal lesions in the liver simultaneously. MAEC of the pancreas with synchronous hepatic metastasis was confirmed with immunohistochemistry after Whipple operation and hepatic partial resection of the lesions. Postoperative recovery of this patient was uneventful, and no evidence of recurrence or metastasis was observed after 12 months of follow-up. MAEC of pancreas is thought to be extremely rare and lack of typical clinical symptoms. The prognosis is poor overall, but early detection with complete resection may be beneficial to patients.
Keywords: acinar cell carcinoma, neuroendocrine carcinoma of pancreas, neuroendocrine carcinoma, pancreatic neoplasms






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