已发表论文

脐血移植辅之以间充质干细胞的输注用于治疗患有重度再生障碍性贫血的青少年患者:病例报告和文献回顾

 

Authors Luan C, Chen R, Chen B, Ding J, Ni M

Published Date June 2015 Volume 2015:9 Pages 759—765

DOI http://dx.doi.org/10.2147/PPA.S81509

Received 24 January 2015, Accepted 26 April 2015, Published 11 June 2015

Approved for publication by Dr Naifeng Liu

Abstract: Delayed hematopoietic recovery and increased rate of engraftment failure limit the use of umbilical cord blood transplantation (UCBT). We describe a case of severe aplastic anemia treated by UCBT combined with mesenchymal stem cells. Our case reveals that infusing mesenchymal stem cells early (about 40 days) after UCBT may promote hematopoietic recovery. This experience will guide clinical scientists, especially hematologists, to deal with similar situations and encourage them to widen this strategy.
Keywords: cord blood transplantation, mesenchymal stem cell, aplastic anemia