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已发表论文
后天性因子 V 抑制剂在头孢他啶 (ceftazidime) 治疗后的发展：病例报告和文献回顾
Authors Cui QY, Shen HS, Wu TQ, Chen HF, Yu ZQ, Wang ZY
Published Date April 2015 Volume 2015:9 Pages 2395—2398
DOI http://dx.doi.org/10.2147/DDDT.S68682
Received 31 May 2014, Accepted 28 August 2014, Published 24 April 2015
Abstract: We report the case of a 59-year-old Chinese man who showed an
asymptomatic coagulation factor V deficiency pattern after second intravenous
treatment with ceftazidime. Normal pooled plasma failed to correct the
abnormalities in a mixing test, and the presence of factor V inhibitor was
confirmed by the Bethesda method. The coagulopathy was not corrected by
transfusion of fresh frozen plasma and prothrombin complex concentrate, but
rather by treatment with prednisone and withdrawal of dubious drugs. The
findings reported here should prompt clinicians to watch for drug-induced
coagulation factor deficiency.
Keywords: acquired factor V deficiency, coagulopathy, prednisone
Keywords: acquired factor V deficiency, coagulopathy, prednisone
