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Authors Wang J, Yang Y, Zha W, Zhang X
Received 30 May 2018
Accepted for publication 3 October 2018
Published 1 November 2018 Volume 2018:11 Pages 7709—7714
DOI https://doi.org/10.2147/OTT.S175825
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 3
Editor who approved publication: Dr Sanjeev Srivastava
Objective: The aim of this study was to investigate the clinical effects and
feasibility of using flexible bronchoscopy intervention in cases of malignancy
that causes central airway stenosis and respiratory failure.
Methods: The clinical data of patients who were admitted to the Department
of Respiratory Medicine at the First Affiliated Hospital of Nanjing Medical
University and underwent treatment of a malignant tumor with central airway
stenosis and respiratory failure by flexible bronchoscopy from February 2010 to
May 2013 were analyzed using a retrospective method. The age, gender, location,
extent of airway stenosis, interventional therapy, efficacy, and complications
for 12 patients were collected and analyzed using the SPSS 13.0 software.
Results: After interventional therapy, the dyspnea index for all the
patients improved significantly, and compared with before treatment, the
difference was statistically significant (t =13.40, P <0.01). Eleven patients with
respiratory failure were corrected, and only one patient was treated via
tracheal intubation with mechanical ventilation. There were no severe
complications, such as massive hemorrhaging or cardiac arrest in any case.
Conclusion: Flexible bronchoscopy interventional treatment for central airway
stenosis and respiratory failure caused by malignant tumors is an effective and
safe method. It should be applied in clinical work.
Keywords: flexible bronchoscopy, malignant tumors, central airway, respiratory
failure, interventional treatment