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结肠镜检查患者晚期结直肠腺瘤的发生率和分布,用于筛查、监测和症状诊查
Authors Kang H, Yang Y, Qiu J, Qian J, Li X
Received 9 May 2018
Accepted for publication 26 July 2018
Published 25 September 2018 Volume 2018:10 Pages 3875—3880
DOI https://doi.org/10.2147/CMAR.S173641
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Justinn Cochran
Peer reviewer comments 3
Editor who approved publication: Dr Antonella D'Anneo
Purpose: The aim of the study was to determine the frequency and distribution of advanced colorectal adenomas (ACAs) in Chinese population.
Methods: The patients who were referred to receive a colonoscopy were divided into three subgroups of screening, surveillance, and symptomatic, and then they were selected based on their indications. The symptomatic subgroup was further broken down into the alarm and non-alarm categories. The location and morphology of all colorectal lesions were both investigated and recorded.
Results: There were significantly more patients with ACAs in the symptomatic subgroup compared to the screening or surveillance subgroup (11.0% vs 4.1%, P <0.001; 11.0% vs 4.6%, P =0.006). No differences were found in the ACA frequency between the alarm and non-alarm categories (11.7% vs 9.7%, P =0.056). One observation was that in the symptomatic subgroup, distal lesions were more likely to contain ACAs than proximal ones (OR 1.50, 95% CI 1.05–2.15, P =0.024). It was also noted that nonpolypoid lesions had significantly higher amounts of ACAs in the symptomatic subgroup (OR 2.09, 95% CI 1.48–2.94, P <0.001) than the other groups.
Conclusion: The incidence of ACAs was higher in patients undergoing a colonoscopy due to their symptoms, compared to the incidence in those who underwent the procedure for screening or surveillance purposes. Additionally, more attention should be focused on distal and nonpolypoid lesions to improve the detection rate of ACAs.
Keywords: advanced colorectal adenomas, incidence, colonoscopy