已发表论文

腹腔镜手术、开放式根治性子宫切除术及盆腔淋巴结切除术在早期宫颈癌治疗中的比较:一项回顾性研究

 

Authors Guo J, Yang L, Cai J, Xu L, Min J, Shen Y, Xiong Z, Dong W, Bunyamanop V, Wang Z

Received 4 November 2017

Accepted for publication 18 March 2018

Published 18 September 2018 Volume 2018:11 Pages 5903—5908

DOI https://doi.org/10.2147/OTT.S156064

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Jianmin Xu

Objective: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias.
Methods: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure.
Results: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups.
Conclusion: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer.
Keywords: early cervical cancer, clinical outcomes, laparoscopic radical hysterectomy, pelvic lymphadenectomy, retrospective study




Figure 1 Kaplan–Meier curves for comparison of survival between groups.