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高压氧治疗改善笑气滥用所致认知功能障碍及脑萎缩的个案报告
Authors Luo D, Xu JJ, Hu L, Yu LM, Xie LL, Li J
Received 3 April 2018
Accepted for publication 29 May 2018
Published 3 August 2018 Volume 2018:14 Pages 1963—1967
DOI https://doi.org/10.2147/NDT.S170037
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Andrew Yee
Peer reviewer comments 3
Editor who approved publication: Professor Wai Kwong Tang
摘要：氧化亚氮，又称笑气，通常用于麻醉，尤其是在口腔和儿科较为常见，目前也供娱乐使用。氧化亚氮滥用引起的认知功能障碍是少见的。今天我们要报告一名 18 岁女性在使用了 5 月的氧化亚氮后出现了脑萎缩及严重的认知功能障碍，用高压氧治疗 20 天后，所有的临床症状逐渐缓解。我们猜测长期大量使用氧化亚氮可能会导致处于慢性的缺氧状态，进一步导致认知功能受损以及脑萎缩。本文首次报告了高压氧治疗 (HBOT) 可能是治疗氧化亚氮滥用所致相关疾病的重要治疗方式。
Keywords: N2O, recreational
use, cognitive dysfunction, encephalatrophy, hyperbaric oxygen therapy
