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Authors Zhu B, Wang Y, Ming J, Chen W, Zhang L
Received 4 January 2018
Accepted for publication 1 March 2018
Published 27 April 2018 Volume 2018:13 Pages 1353—1364
DOI https://doi.org/10.2147/COPD.S161555
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 3
Editor who approved publication: Dr Chunxue Bai
Abstract: Chronic obstructive pulmonary disease (COPD) is one of the main
contributors to the global burden of disease. The aim of this systematic review
was to quantify the disease burden of COPD in China and to determine the risk
factors of the disease. The number of studies included in the review was 47
with an average quality assessment score of 7.70 out of 10. Reported COPD
prevalence varied between 1.20% and 8.87% in different provinces/cities across
China. The prevalence rate of COPD was higher among men (7.76%) than women
(4.07%). The disease was more prevalent in rural areas (7.62%) than in urban
areas (6.09%). The diagnostic rate of COPD patients in China varied from 23.61%
to 30.00%. The percentage of COPD patients receiving outpatient treatment was
around 50%, while the admission rate ranged between 8.78% and 35.60%. Tobacco
exposure and biomass fuel/solid fuel usage were documented as two important
risk factors of COPD. COPD ranked among the top three leading causes of death
in China. The direct medical cost of COPD ranged from 72 to 3,565 USD per
capita per year, accounting for 33.33% to 118.09% of local average annual
income. The most commonly used scales for the assessment of quality of life
(QoL) included Saint George Respiratory Questionnaire, Airways Questionnaire
20, SF-36, and their revised versions. The status of QoL was worse among COPD
patients than in non-COPD patients, and COPD patients were at higher risks of
depression. The COPD burden in China was high in terms of economic burden and
QoL. In view of the high smoking rate and considerable concerns related to air
pollution and smog in China, countermeasures need to be taken to improve
disease prevention and management to reduce disease burdens raised by COPD.
Keywords: COPD, burden of disease, systematic review