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Authors Liu Z, Zhang DY, Lu Z, Zhang P, Sun WL, Ma X, Wu H, Wu BQ, Zhou S
Received 18 January 2018
Accepted for publication 12 March 2018
Published 23 April 2018 Volume 2018:11 Pages 2295—2301
DOI https://doi.org/10.2147/OTT.S162934
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 4
Editor who approved publication: Dr Ingrid Espinoza
Abstract: We report a rare case of neuroendocrine tumor (NET) in the common bile
duct (CBD). The patient is a 56-year-old female who presented to our department
with symptoms of fever but without jaundice. A preoperative examination showed
a tumor in the CBD. The tumor volume was almost 5.5 × 4.5 × 4 cm3, which is the biggest NET in the CBD reported on
PubMed. The imaging results (computed tomography [CT] and magnetic resonance
imaging [MRI]) were not consistent with CBD adenocarcinoma. The tumor appeared
to oppress the growth of the CBD rather than originate in the bile duct wall;
combined with the low blood bilirubin index and lack of jaundice symptoms, the
preoperative diagnosis was not clear. We performed a radical resection of the
cholangiocarcinoma. The patient recovered well before going home. The pathology
was NET (Grade 2). The patient showed no recurrence to date, without
intravenous chemotherapy (8 months).
Keywords: bile duct
adenocarcinoma, neuroendocrine tumors, bile duct