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Authors Lu MX, Min L, Xiao C, Li YJ, Luo Y, Zhou Y, Zhang WL, Tu CQ
Received 14 July 2017
Accepted for publication 20 December 2017
Published 8 February 2018 Volume 2018:10 Pages 265—277
DOI https://doi.org/10.2147/CMAR.S146434
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 2
Editor who approved publication: Dr Antonella D'Anneo
Introduction: Currently, it is challenging to treat giant cell tumor (GCT) of
distal radius. For Campanacci grade III or recurrent GCTs, en bloc resection
has been accepted as a better treatment option. Although numerous methods are
available for reconstruction, all of them have some limitations in joint
function and complications. In this study, our aims were to treat the GCT of
distal radius with uncemented three-dimensional (3D)-printed prosthesis and to
present and evaluate the surgical techniques and short-term outcomes.
Methods: Between September 2015 and March 2017, 11 patients with distal
radius GCTs were treated with personalized uncemented 3D-printed prosthesis.
The preoperative/postoperative pain, range of motion, and grip strengths of all
patients were evaluated. Oncological results, complications, and degenerative
changes in the wrist joint were evaluated. Functional outcomes were assessed
according to the disabilities of the arm, shoulder, and hand (DASH)
questionnaire and Mayo wrist scoring systems.
Results: The average follow-up was 14.45 months (range, 8–18 months). There
was a significant decrease in the mean postoperative visual analog scale score
(2.33) compared with the preoperative score (5.22; p <0.001). The mean DASH score
and Mayo wrist score of the wrist joint function were 18.7 and 72,
respectively. There was no local recurrence or lung metastasis. No complication
associated with prosthesis was observed, including aseptic loosening,
subluxation, and breakage. Joint space narrowing, or disuse osteoporosis, was
also not found in all cases.
Conclusion: En bloc resection and reconstruction with a personalized
uncemented 3D-printed prosthesis can be alternative options to treat Campanacci
grade III or recurrent GCTs of distal radius and can result in short-term
oncologic salvage, good postoperative function, and low complication rate.
However, a long-term follow-up is required to determine the outcome.
Keywords: rapid prototyping, computer-aided design, cementless, uncemented,
polyethylene liner