9 7 8 1 6
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.3 Breast Cancer (Dove Med Press)
- 3.4 Clin Epidemiol
- 2.5 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.5 Clin Interv Aging
- 4.7 Drug Des Dev Ther
- 2.7 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.5 Int J Women's Health
- 2.5 Neuropsych Dis Treat
- 2.7 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.3 Ther Clin Risk Manag
- 2.5 J Pain Res
- 2.8 Diabet Metab Synd Ob
- 2.8 Psychol Res Behav Ma
- 3.0 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.7 Risk Manag Healthc Policy
- 4.2 J Inflamm Res
- 2.1 Int J Gen Med
- 4.2 J Hepatocell Carcinoma
- 3.7 J Asthma Allergy
- 1.9 Clin Cosmet Investig Dermatol
- 2.7 J Multidiscip Healthc
已发表论文
甲状腺切除术后低钙血症和甲状旁腺功能减退的危险因素：对中国人群的回顾性研究
Authors Wang Y, Bhandari A, Yang F, Zhang W, Xue L, Liu H, Zhang X, Chen C
Received 2 August 2017
Accepted for publication 12 October 2017
Published 15 November 2017 Volume 2017:9 Pages 627—635
DOI https://doi.org/10.2147/CMAR.S148090
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 3
Editor who approved publication: Prof. Dr. Alexandra Fernandes
Background: Hypocalcemia is
one of the most common postoperative complications following thyroid surgery in
clinical practice. The occurrence of hypocalcemia is mainly attributed to
hypoparathyroidism when parathyroid glands are devascularized, injured, or
dissected during the surgery. The aim of this study was to analyze the risk
factors for hypocalcemia and hypoparathyroidism following thyroidectomy.
Patients and methods: A total of 278 patients who underwent thyroid surgery were analyzed retrospectively. Univariate analysis and multivariable logistic regression were performed to discover the risk factors for hypocalcemia and hypoparathyroidism.
Results: Postoperative hypocalcemia occurred in 76 (27.3%) patients and hypoparathyroidism occurred in 42 (15.1%) patients. Seven factors were significantly related to the presence of postoperative hypocalcemia, namely, age (P =0.049), gender (P =0.015), lateral lymph node dissection (P =0.017), operation type (P <0.001), preoperative parathyroid hormone (PTH) level (P =0.035), operation time (P =0.001), and applying carbon nanoparticles (CNs; P =0.007). Our result revealed that gender (P =0.014), lateral lymph node dissection (P =0.038), operation type (P <0.001), operative time (P <0.001), and applying CNs (P =0.001) had a significant correlation with postoperative hypoparathyroidism.
Conclusion: These findings were crucial for guiding surgeons to prevent the occurrence of hypocalcemia and hypoparathyroidism.
Keywords: hypocalcemia, hypoparathyroidism, thyroidectomy, risk factor
Patients and methods: A total of 278 patients who underwent thyroid surgery were analyzed retrospectively. Univariate analysis and multivariable logistic regression were performed to discover the risk factors for hypocalcemia and hypoparathyroidism.
Results: Postoperative hypocalcemia occurred in 76 (27.3%) patients and hypoparathyroidism occurred in 42 (15.1%) patients. Seven factors were significantly related to the presence of postoperative hypocalcemia, namely, age (P =0.049), gender (P =0.015), lateral lymph node dissection (P =0.017), operation type (P <0.001), preoperative parathyroid hormone (PTH) level (P =0.035), operation time (P =0.001), and applying carbon nanoparticles (CNs; P =0.007). Our result revealed that gender (P =0.014), lateral lymph node dissection (P =0.038), operation type (P <0.001), operative time (P <0.001), and applying CNs (P =0.001) had a significant correlation with postoperative hypoparathyroidism.
Conclusion: These findings were crucial for guiding surgeons to prevent the occurrence of hypocalcemia and hypoparathyroidism.
Keywords: hypocalcemia, hypoparathyroidism, thyroidectomy, risk factor
