9 7 8 1 6
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.3 Breast Cancer (Dove Med Press)
- 3.4 Clin Epidemiol
- 2.5 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.5 Clin Interv Aging
- 4.7 Drug Des Dev Ther
- 2.7 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.5 Int J Women's Health
- 2.5 Neuropsych Dis Treat
- 2.7 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.3 Ther Clin Risk Manag
- 2.5 J Pain Res
- 2.8 Diabet Metab Synd Ob
- 2.8 Psychol Res Behav Ma
- 3.0 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.7 Risk Manag Healthc Policy
- 4.2 J Inflamm Res
- 2.1 Int J Gen Med
- 4.2 J Hepatocell Carcinoma
- 3.7 J Asthma Allergy
- 1.9 Clin Cosmet Investig Dermatol
- 2.7 J Multidiscip Healthc
已发表论文
The impact of age and preoperative health-related quality of life on patient-reported improvements after total hip arthroplasty
Authors Aalund PK, Glassou EN, Hansen TB
Received 19 August 2017
Accepted for publication 28 September 2017
Published 14 November 2017 Volume 2017:12 Pages 1951—1956
DOI https://doi.org/10.2147/CIA.S149493
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 2
Editor who approved publication: Dr Richard Walker
Background: Total hip arthroplasty
(THA) is a common surgical procedure and approximately 9,500 of these surgeries
are performed annually in Denmark. The operation is considered effective and
successful with respect to complications, mortality, and implant survival.
However, using patient-reported outcome measures, up to 10% of patients are not
satisfied with the outcome of their operation. To address this, it is important
to find out why some patients experience impaired outcomes after THA. The
purpose of this study was to investigate the impact of age and preoperative
health-related quality of life (HRQoL) on improvements in HRQoL after THA.
Methods: A cohort study was conducted with follow-up at 3 and 12 months. Patients were included from September 2008 to December 2013. We analyzed 1,283 THA cases. HRQoL was measured using the EuroQol-5 Domain. Analyses were carried out with multiple linear regression and adjusted for relevant variables available in the data set.
Results: A significant positive association was found between age and HRQoL outcomes for patients who underwent THA at both 3 (β [regression coefficient] 0.0026, confidence interval [CI] 0.0013; 0.0039, p <0.001) and 12 (β 0.0020 CI 0.0008; 0.0032, p =0.001) months of follow-up. A clinically relevant change was achieved with an increase in age of 12–15 years. A significant negative association was found between preoperative HRQoL and HRQoL outcomes at both 3 (β −0.841 CI−0.886; −0.795, p <0.001) and 12 (β −0.804 CI−0.844; −0.764, p <0.001) months of follow-up.
Conclusion: Contrary to our expectations, older patients had more improvements in HRQoL outcomes after THA. A high preoperative HRQoL seems to inhibit improvements in HRQoLs after THA.
Keywords: total hip arthroplasty, THA, health-related quality of life, HRQoL, EuroQol-5D, patient-reported outcome
Methods: A cohort study was conducted with follow-up at 3 and 12 months. Patients were included from September 2008 to December 2013. We analyzed 1,283 THA cases. HRQoL was measured using the EuroQol-5 Domain. Analyses were carried out with multiple linear regression and adjusted for relevant variables available in the data set.
Results: A significant positive association was found between age and HRQoL outcomes for patients who underwent THA at both 3 (β [regression coefficient] 0.0026, confidence interval [CI] 0.0013; 0.0039, p <0.001) and 12 (β 0.0020 CI 0.0008; 0.0032, p =0.001) months of follow-up. A clinically relevant change was achieved with an increase in age of 12–15 years. A significant negative association was found between preoperative HRQoL and HRQoL outcomes at both 3 (β −0.841 CI−0.886; −0.795, p <0.001) and 12 (β −0.804 CI−0.844; −0.764, p <0.001) months of follow-up.
Conclusion: Contrary to our expectations, older patients had more improvements in HRQoL outcomes after THA. A high preoperative HRQoL seems to inhibit improvements in HRQoLs after THA.
Keywords: total hip arthroplasty, THA, health-related quality of life, HRQoL, EuroQol-5D, patient-reported outcome
