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子宫和阔韧带的原发性恶性淋巴瘤：病例报告及文献回顾

 

Authors Chen R, Yu Z, Zhang H, Ding J, Chen B

Published Date January 2015 Volume 2015:8 Pages 265—268

DOI http://dx.doi.org/10.2147/OTT.S78171

Received 26 November 2014, Accepted 20 December 2014, Published 29 January 2015

Abstract: Primary malignant lymphoma of the uterus and broad ligament is rare. Here, we present a rare case of primary diffuse large B-cell lymphoma (DLBCL) of uterus and broad ligament in a 63-year-old female. The patient presenting with lower abdominal distention was referred to our hospital. Subsequent abdominal and pelvic ultrasound revealed the presence of a large mass, which was highly suspected as subserosal uterine leiomyoma. A large tumor was found with unclear boundary with right posterior wall, broad ligament and bilateral adnexa during surgery. Her uterus and the tumor of a broad ligament and bilateral adnexa were all excised as a result. Postoperative pathological examination showed DLBCL in uterus and broad ligament. Further examinations excluded metastatic diseases, which supported the diagnosis of primary DLBCL of the uterus and broad ligament. The patient received six cycles of R-CHOP (21 days) regimen. During the 8 months follow-up, no evidence of disease recurrence was identified. As the prevalence of primary extranodal lymphoma is increasing, the details of this rare case may highlight the importance and facilitate treatment of similar diseases. A summary focusing on the presentation and prognosis as well as a review of current management is also discussed.
Keywords: diffuse large B-cell lymphoma, primary uterine and broad ligament lymphoma, extranodal lymphoma, diagnosis, therapy







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