120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
伴眶内异物的眼球穿通伤临床分析：一项 18 年回顾性研究
Authors Niu L, Ren H, Xu H , Sun X , Jiang R
Received 15 December 2025
Accepted for publication 2 February 2026
Published 7 February 2026 Volume 2026:20 586656
DOI https://doi.org/10.2147/OPTH.S586656
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Scott Fraser
Liangliang Niu,1– 4,* Hui Ren,1– 3,* Huan Xu,1– 4 Xinghuai Sun,1– 3,5 Rui Jiang1– 4
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China; 2NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, People’s Republic of China; 3Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, People’s Republic of China; 4Ocular Trauma Center, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China; 5State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, 200032, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xinghuai Sun, Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China, Email xhsun@shmu.edu.cn Rui Jiang, Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China, Email 2jiang@163.com
Purpose: This study investigated the clinical characteristics, management strategies, and visual outcomes of perforating ocular injuries associated with intraorbital foreign bodies (IOrFBs).
Methods: We retrospectively reviewed 54 patients with perforating ocular injuries and IOrFBs admitted to the Eye & ENT Hospital of Fudan University from January 1, 2007, to December 31, 2024. This study was reviewed and approved by the Ethics Committee of the Eye & ENT Hospital of Fudan University (Approval No. 2024146). Data collected included demographics, injury circumstances, foreign body composition, size and location (measured on preoperative computed tomography [CT] images), surgical approaches, and visual outcomes. Statistical analyses were performed using R, with significance set at p < 0.05.
Results: Of the 54 patients, 87.0% (47) were male, and 92.6% (50) sustained occupational injuries (both p < 0.001). Ferromagnetic metallic fragments were the predominant cause (77.8%, 42). Anatomically, 40.7% (22) of foreign bodies were confined to the orbit, while 18.5% (10) involved the inferior globe wall and 16.7% (9) extended to the posterior pole. Larger IOrFB diameters were significantly associated with poorer preoperative and postoperative visual acuity (p < 0.05). Surgical interventions were performed as either single-stage or staged procedures, depending on the severity of the injury. The surgical strategies included pars plana vitrectomy (PPV) alone without foreign body removal; PPV combined with IOrFB extraction; PPV followed by subsequent orbital surgery for foreign body removal; orbital surgery for foreign body extraction followed by subsequent PPV; and IOrFB extraction alone without PPV. The most common surgical approach was combined PPV with orbital surgery (35.2%, 19). Notably, surgical approach was not an independent predictor of final visual outcomes.
Conclusion: IOrFBs primarily affect working-age men and are typically caused by occupational metallic trauma. Larger foreign bodies predict worse baseline and final vision, whereas foreign body location and surgical approach do not independently influence visual prognosis. These findings highlight the need for early detection, occupational safety measures, and individualized management to optimize outcomes.
Keywords: open-globe injury, perforating ocular trauma, intraorbital foreign body, surgical strategy, visual acuity
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China; 2NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, People’s Republic of China; 3Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, People’s Republic of China; 4Ocular Trauma Center, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China; 5State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, 200032, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xinghuai Sun, Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China, Email xhsun@shmu.edu.cn Rui Jiang, Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, People’s Republic of China, Email 2jiang@163.com
Purpose: This study investigated the clinical characteristics, management strategies, and visual outcomes of perforating ocular injuries associated with intraorbital foreign bodies (IOrFBs).
Methods: We retrospectively reviewed 54 patients with perforating ocular injuries and IOrFBs admitted to the Eye & ENT Hospital of Fudan University from January 1, 2007, to December 31, 2024. This study was reviewed and approved by the Ethics Committee of the Eye & ENT Hospital of Fudan University (Approval No. 2024146). Data collected included demographics, injury circumstances, foreign body composition, size and location (measured on preoperative computed tomography [CT] images), surgical approaches, and visual outcomes. Statistical analyses were performed using R, with significance set at p < 0.05.
Results: Of the 54 patients, 87.0% (47) were male, and 92.6% (50) sustained occupational injuries (both p < 0.001). Ferromagnetic metallic fragments were the predominant cause (77.8%, 42). Anatomically, 40.7% (22) of foreign bodies were confined to the orbit, while 18.5% (10) involved the inferior globe wall and 16.7% (9) extended to the posterior pole. Larger IOrFB diameters were significantly associated with poorer preoperative and postoperative visual acuity (p < 0.05). Surgical interventions were performed as either single-stage or staged procedures, depending on the severity of the injury. The surgical strategies included pars plana vitrectomy (PPV) alone without foreign body removal; PPV combined with IOrFB extraction; PPV followed by subsequent orbital surgery for foreign body removal; orbital surgery for foreign body extraction followed by subsequent PPV; and IOrFB extraction alone without PPV. The most common surgical approach was combined PPV with orbital surgery (35.2%, 19). Notably, surgical approach was not an independent predictor of final visual outcomes.
Conclusion: IOrFBs primarily affect working-age men and are typically caused by occupational metallic trauma. Larger foreign bodies predict worse baseline and final vision, whereas foreign body location and surgical approach do not independently influence visual prognosis. These findings highlight the need for early detection, occupational safety measures, and individualized management to optimize outcomes.
Keywords: open-globe injury, perforating ocular trauma, intraorbital foreign body, surgical strategy, visual acuity