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已发表论文
难治性荨麻疹性血管炎的治疗挑战
Received 8 November 2025
Accepted for publication 25 January 2026
Published 7 February 2026 Volume 2026:19 579985
DOI https://doi.org/10.2147/CCID.S579985
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jeffrey Weinberg
Lisha Sun,1 Qiao Yu,2 Xinlong Chen2
1Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China
Correspondence: Xinlong Chen, Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email drxinlongchen@163.com
Abstract: Urticarial vasculitis, a rare autoimmune disease, is characterized by inflammation of the small blood vessels. It presents with skin lesions that resemble hives, but unlike ordinary hives, these lesions last longer than 24 hours, may leave behind bruise-like discoloration or purpura, and can be associated with systemic symptoms. This case reports details a middle-aged female patient, who exhibited extensive urticarial lesions persisting for two weeks and severe reactions to initial treatments.
Keywords: refractory urticarial vasculitis, omalizumab, immunosuppressants
1Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China
Correspondence: Xinlong Chen, Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email drxinlongchen@163.com
Abstract: Urticarial vasculitis, a rare autoimmune disease, is characterized by inflammation of the small blood vessels. It presents with skin lesions that resemble hives, but unlike ordinary hives, these lesions last longer than 24 hours, may leave behind bruise-like discoloration or purpura, and can be associated with systemic symptoms. This case reports details a middle-aged female patient, who exhibited extensive urticarial lesions persisting for two weeks and severe reactions to initial treatments.
Keywords: refractory urticarial vasculitis, omalizumab, immunosuppressants