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已发表论文
加速康复外科指导下护理干预在肺结节切除患者中的应用
Received 8 October 2025
Accepted for publication 10 January 2026
Published 10 February 2026 Volume 2026:19 572877
DOI https://doi.org/10.2147/JMDH.S572877
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Pavani Rangachari
Yan Liu, Xuehui Wang, Yuyou Yao
Health Management Center, the Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214023, People’s Republic of China
Correspondence: Yuyou Yao, Email yaoyuyou@njmu.edu.cn
Background: The Enhanced Recovery After Surgery (ERAS) protocol has shown promise in improving postoperative outcomes, but its specific impact on pulmonary nodule resection has not been well explored. In this retrospective cohort study with propensity score matching, we evaluated the association between ERAS-guided care and postoperative outcomes after pulmonary nodule resection.
Methods: Patients undergoing pulmonary nodule resection were retrospectively enrolled, and 168 propensity score–matched patients were analyzed. The included patients were divided into the control group receiving conventional nursing care and the ERAS group receiving care guided by the ERAS protocol. Postoperative complications, stress response indicators, including C-reactive protein (CRP) and interleukin-6 (IL-6), as well as pulmonary function parameters, were evaluated.
Results: A significantly lower overall complication rate was observed in the ERAS group (5.9% vs 20.5%, p = 0.006) compared to the control group. Additionally, the ERAS group demonstrated a shorter postoperative drainage duration, shorter tracheal extubation time, and a decreased length of stay. Postoperative pulmonary function, as assessed by Forced Vital Capacity (FVC%), Forced Expiratory Volume in 1 second (FEV1%), and the FEV1/FVC ratio, was significantly improved in the ERAS group (FVC%: 76.92 ± 11.68 vs 70.57 ± 11.92, p < 0.001; FEV1%: 68.97 ± 9.44 vs 63.53 ± 9.66, p < 0.001), indicating superior recovery. Furthermore, serum CRP and IL-6 levels were significantly lower in the ERAS group at 48 h postoperatively (p < 0.001 for both), suggesting a reduced inflammatory response.
Conclusion: ERAS protocols are associated with significantly improved postoperative recovery following pulmonary nodule resection, including reduced complications, enhanced pulmonary function recovery and decreased inflammatory markers.
Keywords: pulmonary nodule resection, enhanced recovery after surgery, pulmonary function, complication, inflammation
Health Management Center, the Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214023, People’s Republic of China
Correspondence: Yuyou Yao, Email yaoyuyou@njmu.edu.cn
Background: The Enhanced Recovery After Surgery (ERAS) protocol has shown promise in improving postoperative outcomes, but its specific impact on pulmonary nodule resection has not been well explored. In this retrospective cohort study with propensity score matching, we evaluated the association between ERAS-guided care and postoperative outcomes after pulmonary nodule resection.
Methods: Patients undergoing pulmonary nodule resection were retrospectively enrolled, and 168 propensity score–matched patients were analyzed. The included patients were divided into the control group receiving conventional nursing care and the ERAS group receiving care guided by the ERAS protocol. Postoperative complications, stress response indicators, including C-reactive protein (CRP) and interleukin-6 (IL-6), as well as pulmonary function parameters, were evaluated.
Results: A significantly lower overall complication rate was observed in the ERAS group (5.9% vs 20.5%, p = 0.006) compared to the control group. Additionally, the ERAS group demonstrated a shorter postoperative drainage duration, shorter tracheal extubation time, and a decreased length of stay. Postoperative pulmonary function, as assessed by Forced Vital Capacity (FVC%), Forced Expiratory Volume in 1 second (FEV1%), and the FEV1/FVC ratio, was significantly improved in the ERAS group (FVC%: 76.92 ± 11.68 vs 70.57 ± 11.92, p < 0.001; FEV1%: 68.97 ± 9.44 vs 63.53 ± 9.66, p < 0.001), indicating superior recovery. Furthermore, serum CRP and IL-6 levels were significantly lower in the ERAS group at 48 h postoperatively (p < 0.001 for both), suggesting a reduced inflammatory response.
Conclusion: ERAS protocols are associated with significantly improved postoperative recovery following pulmonary nodule resection, including reduced complications, enhanced pulmonary function recovery and decreased inflammatory markers.
Keywords: pulmonary nodule resection, enhanced recovery after surgery, pulmonary function, complication, inflammation