120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
浓缩生长因子治疗填充剂诱导性脱发
Authors Zhang L, Li J, Fu X, Liu H , Zhang F
Received 29 October 2025
Accepted for publication 23 January 2026
Published 2 February 2026 Volume 2026:19 565211
DOI https://doi.org/10.2147/CCID.S565211
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 4
Editor who approved publication: Dr Michela Starace
LiHong Zhang,1,2 JianKe Li,1,2 Xi’An Fu,1,2 Hong Liu,1,2 FuRen Zhang1,2
1Medical Aesthetics Department, Dermatology Hospital of Shandong First Medical University, Jinan, Shandong, People’s Republic of China; 2Medical Aesthetics Department, Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Science, Jinan, Shandong, People’s Republic of China
Correspondence: Xi’An Fu, Medical Aesthetics Department, Dermatology Hospital of Shandong First Medical University, No. 27397 Jingshi Road, Jinan, Shandong, People’s Republic of China, 250022, Tel +86-13455109433, Email f19830827@126.com
Abstract: Hyaluronic acid (HA) is widely used for non-surgical facial rejuvenation but is associated with risks, including rare filler-induced alopecia (FIA) in the temporal and frontal regions. While subcutaneous hyaluronidase (HAase) injection is the standard treatment, we report an alternative approach using concentrated growth factor (CGF) injections. A 29-year-old female presented with a pruritic alopecic patch in the right temporal region that appeared 20 days after receiving HA filler injection. A well-demarcated 6× 4 cm alopecic patch persisted despite prior treatment with HAase. The patient subsequently underwent four CGF injections. During the ten-month follow-up, significant hair regrowth was observed. This case suggests that CGF monotherapy is a promising treatment for FIA.
Keywords: alopecia, hyaluronic acid, concentrated growth factors, filler complication
1Medical Aesthetics Department, Dermatology Hospital of Shandong First Medical University, Jinan, Shandong, People’s Republic of China; 2Medical Aesthetics Department, Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Science, Jinan, Shandong, People’s Republic of China
Correspondence: Xi’An Fu, Medical Aesthetics Department, Dermatology Hospital of Shandong First Medical University, No. 27397 Jingshi Road, Jinan, Shandong, People’s Republic of China, 250022, Tel +86-13455109433, Email f19830827@126.com
Abstract: Hyaluronic acid (HA) is widely used for non-surgical facial rejuvenation but is associated with risks, including rare filler-induced alopecia (FIA) in the temporal and frontal regions. While subcutaneous hyaluronidase (HAase) injection is the standard treatment, we report an alternative approach using concentrated growth factor (CGF) injections. A 29-year-old female presented with a pruritic alopecic patch in the right temporal region that appeared 20 days after receiving HA filler injection. A well-demarcated 6× 4 cm alopecic patch persisted despite prior treatment with HAase. The patient subsequently underwent four CGF injections. During the ten-month follow-up, significant hair regrowth was observed. This case suggests that CGF monotherapy is a promising treatment for FIA.
Keywords: alopecia, hyaluronic acid, concentrated growth factors, filler complication