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已发表论文
基于网络定量视野计（Perimouse）的开角型青光眼居家视野监测：一项为期六个月的评估
Authors Shen X, Chen Z, Yang W, Wang M, Tan K , Fan Y, Liu P, Ye J, Ouyang Z, Zheng G, Yang Y, Yu M
Received 17 November 2025
Accepted for publication 27 January 2026
Published 2 February 2026 Volume 2026:20 582204
DOI https://doi.org/10.2147/OPTH.S582204
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Scott Fraser
Xiaoyuan Shen,1,* Zidong Chen,1,* Wenxin Yang,1 Mingqin Wang,1 Kaixin Tan,1 Yanmei Fan,1 Pingping Liu,1 Jiexin Ye,2 Zhiqiang Ouyang,2 Guifeng Zheng,2 Yangfan Yang,1 Minbin Yu1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China; 2School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Minbin Yu, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China, Tel +8620 6661 5460, Fax +8620 3761 9853, Email yuminbin@mail.sysu.edu.cn
Purpose: To assess the reliability and acceptability of home-based visual field monitoring in glaucoma patients using a self-developed online perimeter (Perimouse).
Patients and Methods: In this prospective study, patients with stable open-angle glaucoma conducted monthly remote visual field tests using the Perimouse threshold program in an unsupervised home setting over six months, with Humphrey Field Analyzer (HFA) tests performed before and after the trial. The study evaluated patient compliance with Perimouse and compared its stability and variability to HFA. Additionally, a questionnaire assessed patient acceptability of Perimouse.
Results: Sixty glaucoma patients (97 eyes) participated in this study. The follow-up completion rate of home tests remained 67.01% in the sixth month despite a gradual decline over time. A pointwise analysis demonstrated overall consistency, although variability increased as sensitivity decreased. Bland–Altman analysis of Perimouse mean deviation (MD) showed that the mean differences between Month 1 and Months 2– 6 were close to zero. The mean absolute error for Perimouse MD ranged from 0.71 to 1.04, compared to 0.55 for HFA. Perimouse test duration decreased over six months, from 10.04 ± 2.74 minutes to 8.31 ± 2.77 minutes. The questionnaire indicated that Perimouse scoring higher than HFA in stress relief, visual comfort, and cost-effectiveness (P< 0.05).
Conclusion: This study showed that participants could perform Perimouse remotely in an unsupervised setting with video and written instructions. Perimouse may support home-based visual field monitoring and enhance self-management for glaucoma patients.
Keywords: telemedicine, remote patient monitoring, glaucoma, visual field tests
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China; 2School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Minbin Yu, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People’s Republic of China, Tel +8620 6661 5460, Fax +8620 3761 9853, Email yuminbin@mail.sysu.edu.cn
Purpose: To assess the reliability and acceptability of home-based visual field monitoring in glaucoma patients using a self-developed online perimeter (Perimouse).
Patients and Methods: In this prospective study, patients with stable open-angle glaucoma conducted monthly remote visual field tests using the Perimouse threshold program in an unsupervised home setting over six months, with Humphrey Field Analyzer (HFA) tests performed before and after the trial. The study evaluated patient compliance with Perimouse and compared its stability and variability to HFA. Additionally, a questionnaire assessed patient acceptability of Perimouse.
Results: Sixty glaucoma patients (97 eyes) participated in this study. The follow-up completion rate of home tests remained 67.01% in the sixth month despite a gradual decline over time. A pointwise analysis demonstrated overall consistency, although variability increased as sensitivity decreased. Bland–Altman analysis of Perimouse mean deviation (MD) showed that the mean differences between Month 1 and Months 2– 6 were close to zero. The mean absolute error for Perimouse MD ranged from 0.71 to 1.04, compared to 0.55 for HFA. Perimouse test duration decreased over six months, from 10.04 ± 2.74 minutes to 8.31 ± 2.77 minutes. The questionnaire indicated that Perimouse scoring higher than HFA in stress relief, visual comfort, and cost-effectiveness (P< 0.05).
Conclusion: This study showed that participants could perform Perimouse remotely in an unsupervised setting with video and written instructions. Perimouse may support home-based visual field monitoring and enhance self-management for glaucoma patients.
Keywords: telemedicine, remote patient monitoring, glaucoma, visual field tests