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HIV 阳性患者使用 Biktarvy 并饮酒后高脂血症继发急性胰腺炎:一例病例报告

 

Authors Zheng R, Zhang Z , Yan J, Li F, Shi J 

Received 14 November 2025

Accepted for publication 28 January 2026

Published 2 February 2026 Volume 2026:19 581484

DOI https://doi.org/10.2147/IMCRJ.S581484

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Thomas E Hutson

Rongrong Zheng, Zhongdong Zhang, Jun Yan, Feng Li, Jinchuan Shi

The Second Infectious Disease Department, Xixi Hospital of Hangzhou, Hangzhou, 310023, People’s Republic of China

Correspondence: Jinchuan Shi, The Second Infectious Disease Department, Xixi Hospital of Hangzhou, No. 2 Hengbu Street, Liuxia Town, Xihu District, Hangzhou, 310023, People’s Republic of China, Email shijinchuan2008@126.com

Abstract: The etiology of acute pancreatitis is multifactorial. Hypertriglyceridemia is the third most common cause of acute pancreatitis. Biktarvy, a recently approved human immunodeficiency virus (HIV) treatment, is a single tablet regimen in combination with bictegravir, emtricitabine, and tenofovir alafenamide (BIC/FTC/TAF). A multitude of studies have identified a high risk of weight gain and hyperlipidemia, a trigger for acute pancreatitis, with Biktarvy use. This is the inaugural case of acquired immunodeficiency syndrome (AIDS) with acute pancreatitis as a secondary complication of Biktarvy and alcohol exposure, accompanied by cholelithiasis and diabetes. This case highlights the need for lipid monitoring in patients on Tenofovir Alafenamide (TAF)-based regimens.

Keywords: HIV, acute pancreatitis, hyperlipidemia, BIC/FTC/TAF