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已发表论文
腺肌病高强度聚焦超声与腹腔镜全子宫切除术后女性性功能障碍：与焦虑和抑郁的关联
Authors Zhao X, Wang H, Feng L, Wang H, Wang Y, Mi M, Zhang W
Received 10 November 2025
Accepted for publication 24 January 2026
Published 2 February 2026 Volume 2026:18 576959
DOI https://doi.org/10.2147/IJWH.S576959
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Vinay Kumar
Xiaoli Zhao,1,* Hongbin Wang,2,* Li Feng,1 Haixing Wang,1 Yiqian Wang,1 Meiyan Mi,1 Wei Zhang1
1Department of Gynecology, the Fourth Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000, People’s Republic of China; 2Department of Obstetrics, the Fourth Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Meiyan Mi, Email sjzfcyy_china@126.com Wei Zhang, Email sjzdsyychina@126.com
Background: Direct comparative data on postoperative sexual function between laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) in adenomyosis (AM) remain limited; therefore, this retrospective study compared sexual outcomes and their associations with psychological factors.
Methods and Materials: Medical records of 193 AM patients who underwent either LTH (n=102) or HIFU (n=91) and completed six-month follow-up were retrospectively reviewed. Sexual function was evaluated using the Female Sexual Function Index (FSFI), while psychological status was assessed using the Hamilton Anxiety Rating Scale (HAMA) and the Hamilton Depression Rating Scale (HAMD).
Results: HIFU group demonstrated significantly higher total FSFI scores when compared with LTH group at 6 months post-treatment (27.3 vs 23.8, p< 0.001). Significant improvements were found in sexual desire (4.2 vs 3.6, p< 0.001), lubrication (4.0 vs 3.5, p< 0.05), orgasm (3.8 vs 3.2, p< 0.001), and satisfaction (3.3 vs 2.7, p< 0.001), while similar trend was observed in pain scores. It was further demonstrated that elevated anxiety and depression scores were negatively correlated with FSFI scores (r=− 0.39 and − 0.37, both p< 0.001).
Conclusion: HIFU was associated with better sexual function compared to LTH in AM women, suggesting that HIFU may be a better strategy to preserve postoperative sexual function than LTH.
Keywords: adenomyosis, sexual dysfunction, HIFU, LTH, psychological factors
1Department of Gynecology, the Fourth Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000, People’s Republic of China; 2Department of Obstetrics, the Fourth Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Meiyan Mi, Email sjzfcyy_china@126.com Wei Zhang, Email sjzdsyychina@126.com
Background: Direct comparative data on postoperative sexual function between laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) in adenomyosis (AM) remain limited; therefore, this retrospective study compared sexual outcomes and their associations with psychological factors.
Methods and Materials: Medical records of 193 AM patients who underwent either LTH (n=102) or HIFU (n=91) and completed six-month follow-up were retrospectively reviewed. Sexual function was evaluated using the Female Sexual Function Index (FSFI), while psychological status was assessed using the Hamilton Anxiety Rating Scale (HAMA) and the Hamilton Depression Rating Scale (HAMD).
Results: HIFU group demonstrated significantly higher total FSFI scores when compared with LTH group at 6 months post-treatment (27.3 vs 23.8, p< 0.001). Significant improvements were found in sexual desire (4.2 vs 3.6, p< 0.001), lubrication (4.0 vs 3.5, p< 0.05), orgasm (3.8 vs 3.2, p< 0.001), and satisfaction (3.3 vs 2.7, p< 0.001), while similar trend was observed in pain scores. It was further demonstrated that elevated anxiety and depression scores were negatively correlated with FSFI scores (r=− 0.39 and − 0.37, both p< 0.001).
Conclusion: HIFU was associated with better sexual function compared to LTH in AM women, suggesting that HIFU may be a better strategy to preserve postoperative sexual function than LTH.
Keywords: adenomyosis, sexual dysfunction, HIFU, LTH, psychological factors