120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
永久性心脏起搏器植入后早期心脏康复的安全性和有效性评估：一项初步研究
Authors Wu X, Wang X, Cao M, Wang Y, Pan J, Xiao M, Zheng M
Received 26 August 2025
Accepted for publication 10 January 2026
Published 4 February 2026 Volume 2026:19 563336
DOI https://doi.org/10.2147/JMDH.S563336
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Pavani Rangachari
Xiaoqiu Wu,1,* Xiaofei Wang,2,* Meiying Cao,3 Yongguang Wang,3 Jiaxi Pan,3 Mengchun Xiao,3 Mengmeng Zheng3
1Department of Gastroenterology, Ward, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China; 2Department of Gastrointestinal Surgery, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China; 3Department of Cardiovascular Medicine, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Mengchun Xiao, Department of Cardiovascular Medicine, Rui’an People’s Hospital, No. 108, Wansong Road, Rui’an, Wenzhou, Zhejiang Province, 325200, People’s Republic of China, Email mmgwc1yyj@163.com Mengmeng Zheng, Department of Cardiovascular Medicine, Rui’an People’s Hospital, No. 108, Wansong Road, Rui’an, Wenzhou, Zhejiang Province, 325200, People’s Republic of China, Email iazmm@163.com
Background: This pilot study aimed to evaluate the safety, feasibility, and preliminary effectiveness of early supervised cardiac rehabilitation (CR) initiated within 7 days after permanent pacemaker implantation.
Methods: A prospective, non-randomized pilot study was conducted using consecutive sampling to enroll 100 adults undergoing first-time pacemaker implantation. Participants were assigned to either an early CR group or standard care. The primary outcome was safety, including lead dislodgement, arrhythmia, or syncope. Secondary outcomes included changes in 6-minute walk distance (6MWT), SF-36, and HADS scores.
Results: No exercise-related adverse events occurred. Compared with standard care, the early CR group showed greater improvement in 6MWT distance (mean difference: +62.4 m; 95% CI: 38.1– 86.7; p < 0.01), SF-36 PCS (+5.0; 95% CI: 0.7– 8.9; p = 0.03), and HADS-anxiety (– 2.4; 95% CI: – 4.6 to – 0.2; p = 0.04).
Conclusion: Early CR after pacemaker implantation appears safe, feasible, and associated with improved functional capacity and psychological well-being. Limitations include the non-randomized design, single-center setting, and short follow-up. Larger randomized trials are needed.
Keywords: Pacemaker, cardiac rehabilitation, exercise therapy, functional recovery, pilot study
1Department of Gastroenterology, Ward, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China; 2Department of Gastrointestinal Surgery, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China; 3Department of Cardiovascular Medicine, Rui’an People’s Hospital, Rui’an, Wenzhou, 325200, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Mengchun Xiao, Department of Cardiovascular Medicine, Rui’an People’s Hospital, No. 108, Wansong Road, Rui’an, Wenzhou, Zhejiang Province, 325200, People’s Republic of China, Email mmgwc1yyj@163.com Mengmeng Zheng, Department of Cardiovascular Medicine, Rui’an People’s Hospital, No. 108, Wansong Road, Rui’an, Wenzhou, Zhejiang Province, 325200, People’s Republic of China, Email iazmm@163.com
Background: This pilot study aimed to evaluate the safety, feasibility, and preliminary effectiveness of early supervised cardiac rehabilitation (CR) initiated within 7 days after permanent pacemaker implantation.
Methods: A prospective, non-randomized pilot study was conducted using consecutive sampling to enroll 100 adults undergoing first-time pacemaker implantation. Participants were assigned to either an early CR group or standard care. The primary outcome was safety, including lead dislodgement, arrhythmia, or syncope. Secondary outcomes included changes in 6-minute walk distance (6MWT), SF-36, and HADS scores.
Results: No exercise-related adverse events occurred. Compared with standard care, the early CR group showed greater improvement in 6MWT distance (mean difference: +62.4 m; 95% CI: 38.1– 86.7; p < 0.01), SF-36 PCS (+5.0; 95% CI: 0.7– 8.9; p = 0.03), and HADS-anxiety (– 2.4; 95% CI: – 4.6 to – 0.2; p = 0.04).
Conclusion: Early CR after pacemaker implantation appears safe, feasible, and associated with improved functional capacity and psychological well-being. Limitations include the non-randomized design, single-center setting, and short follow-up. Larger randomized trials are needed.
Keywords: Pacemaker, cardiac rehabilitation, exercise therapy, functional recovery, pilot study