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已发表论文
合并焦虑障碍的 38 岁女性人为性皮炎：诊断挑战及多学科管理的重要性
Authors Wang J , Zhou X, Chen X
Received 6 December 2025
Accepted for publication 1 February 2026
Published 5 February 2026 Volume 2026:19 587040
DOI https://doi.org/10.2147/CCID.S587040
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jeffrey Weinberg
Jue Wang,1,* Xinyu Zhou,2,* Xinlong Chen1
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Department of Dermatology, Nanbu People’s Hospital, Nanchong, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xinlong Chen, Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China, Email drxinlongchen@163.com
Abstract: Dermatitis artefacta (DA) is a psychocutaneous disorder characterized by self-inflicted skin lesions and frequently associated with underlying psychological distress. We report a case of a 38-year-old woman who presented with recurrent erythema, papules, exudation, and severe pruritus involving the head and neck for over one year. The patient was initially misdiagnosed with atopic dermatitis and treated with immunosuppressive therapy, partly due to overlapping clinical features and the presence of peripheral eosinophilia, which was misinterpreted as evidence of allergic inflammation. Further evaluation revealed significant comorbid anxiety, and the diagnosis of dermatitis artefacta was established based on clinical morphology, disease course, behavioral features, and response to combined dermatological and psychiatric management. This case highlights how nonspecific laboratory abnormalities, such as eosinophilia, may contribute to diagnostic delay and inappropriate treatment escalation if psychocutaneous disorders are not considered. Early recognition of dermatitis artefacta and timely integration of psychological assessment are essential to prevent misdiagnosis and unnecessary immunosuppressive therapy in patients with atypical or treatment-refractory dermatoses.
Keywords: dermatitis, artefacta, anxiety, disorder
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Department of Dermatology, Nanbu People’s Hospital, Nanchong, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xinlong Chen, Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China, Email drxinlongchen@163.com
Abstract: Dermatitis artefacta (DA) is a psychocutaneous disorder characterized by self-inflicted skin lesions and frequently associated with underlying psychological distress. We report a case of a 38-year-old woman who presented with recurrent erythema, papules, exudation, and severe pruritus involving the head and neck for over one year. The patient was initially misdiagnosed with atopic dermatitis and treated with immunosuppressive therapy, partly due to overlapping clinical features and the presence of peripheral eosinophilia, which was misinterpreted as evidence of allergic inflammation. Further evaluation revealed significant comorbid anxiety, and the diagnosis of dermatitis artefacta was established based on clinical morphology, disease course, behavioral features, and response to combined dermatological and psychiatric management. This case highlights how nonspecific laboratory abnormalities, such as eosinophilia, may contribute to diagnostic delay and inappropriate treatment escalation if psychocutaneous disorders are not considered. Early recognition of dermatitis artefacta and timely integration of psychological assessment are essential to prevent misdiagnosis and unnecessary immunosuppressive therapy in patients with atypical or treatment-refractory dermatoses.
Keywords: dermatitis, artefacta, anxiety, disorder