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已发表论文
已获批抗肿瘤中成药的特性：整合证据与传统
Authors Qi L , Qian S, Wang L, Liu Z, Jiang J, Liu C, Pan Y, Wang B, Han X, Chen J
Received 20 October 2025
Accepted for publication 27 January 2026
Published 5 February 2026 Volume 2026:20 575608
DOI https://doi.org/10.2147/DDDT.S575608
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Leonidas D. Panos
Linlin Qi,1,* Shushu Qian,2,* Ling Wang,1,* Zhixu Liu,1 Jiaxin Jiang,1 Chunmei Liu,3 Yang Pan,3 Bo Wang,4 Xuan Han,1,5 Jing Chen1
1National Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Department of Rehabilitation Medicine, Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, People’s Republic of China; 3College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 4Department of Biopharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China; 5School of Integrated Medicine, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xuan Han, Email hanxuan@njucm.edu.cn Jing Chen, Email jingchen3236@njucm.edu.cn
Abstract: The properties and meridian affinities of Chinese herbal medicine are closely associated with their therapeutic efficacy. This review focuses on approved antitumour Chinese medicines listed in the Pharmacopoeia of the People’s Republic of China (2020 Edition, Volume I), highlighting their key components. Statistical methods were used to analyse the properties, flavours and channel tropisms of antitumour traditional Chinese medicine (TCM), including both proprietary formulations and commercially available individual herbs. Distinctive patterns were identified by comparing herb profiles with contemporary experimental studies on antitumour TCM. Analysis revealed that bitter-cold herbs represented the highest proportion of antitumour TCM, with most showing tropism towards the liver channel. These findings provide a reference framework for antitumour drug development, indicating that bitter-cold herbs merit priority as candidate ingredients.
Keywords: antitumour traditional chinese medicine, properties, flavours, channel tropism
1National Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Department of Rehabilitation Medicine, Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, People’s Republic of China; 3College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 4Department of Biopharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China; 5School of Integrated Medicine, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xuan Han, Email hanxuan@njucm.edu.cn Jing Chen, Email jingchen3236@njucm.edu.cn
Abstract: The properties and meridian affinities of Chinese herbal medicine are closely associated with their therapeutic efficacy. This review focuses on approved antitumour Chinese medicines listed in the Pharmacopoeia of the People’s Republic of China (2020 Edition, Volume I), highlighting their key components. Statistical methods were used to analyse the properties, flavours and channel tropisms of antitumour traditional Chinese medicine (TCM), including both proprietary formulations and commercially available individual herbs. Distinctive patterns were identified by comparing herb profiles with contemporary experimental studies on antitumour TCM. Analysis revealed that bitter-cold herbs represented the highest proportion of antitumour TCM, with most showing tropism towards the liver channel. These findings provide a reference framework for antitumour drug development, indicating that bitter-cold herbs merit priority as candidate ingredients.
Keywords: antitumour traditional chinese medicine, properties, flavours, channel tropism