已发表论文

硬膜外分娩镇痛产妇头位难产风险预测模型的建立与验证

 

Authors Han Y, Liu Z, Gan Y, Tan X, Diao Q, Cao Y, Shi Q

Received 13 August 2025

Accepted for publication 3 January 2026

Published 24 January 2026 Volume 2026:18 560398

DOI https://doi.org/10.2147/IJWH.S560398

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Everett Magann

Yu Han,* Zengying Liu,* Yanqiong Gan, Xinlin Tan, Qiuyue Diao, Yuting Cao, Qi Shi

Department of Obstetrics, The Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Qi Shi, Department of Obstetrics, The Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan, 637000, People’s Republic of China, Tel +86-15983789947, Email shiqistone@163.com

Background: While effectively relieving labor pain, epidural analgesia may decrease signs of cephalic dystocia, delaying timely diagnosis and intervention.
Objective: Develop and validate a prediction model for cephalic dystocia risk under epidural analgesia.
Methods: Between January 2021 and October 2024, 855 women who gave birth at the Obstetrics Department of the Affiliated Hospital of North Sichuan Medical College and received epidural analgesia were included in this study. To identify independent risk factors, univariate and multivariate logistic regression analyses were conducted and R software was used to construct a nomogram prediction model. ROC curve analysis, Hosmer-Lemeshow (H-L) tests, calibration plots, and decision curve analysis were used to evaluate the predictive ability of the model. Bootstrap resampling was used for internal validation.
Results: The following factors were found to be independent predictors of cephalic dystocia under epidural analgesia: premature rupture of membranes (OR: 2.73, 95% CI: 1.46– 5.11), prolonged latent phase (OR: 13.82, 95% CI: 7.51– 25.42),fetal abdominal circumference (OR: 5.13, 95% CI: 2.22– 11.81), maternal age (OR:3.87, 95% CI:1.29– 11.59), parity (OR: 16.16, 95% CI: 2.95– 88.55), fetal presentation at the early stage of the active phase (OR: 2.82, 95% CI: 1.63– 4.88), and fetal position at the early stage of the active phase (OR:8.4, 95% CI:4.83– 14.59). The area under the curve (AUC) for this predictive model was 0.910 (95% CI: 0.878– 0.941). The Hosmer-Lemeshow goodness-of-fit test and calibration curve results showed that (P=0.992 > 0.05). Within the clinical decision curve, the net benefit of the nomogram model is higher across the threshold probability range of 0.05 to 0.83.
Conclusion: This risk prediction model can identify high-risk cephalic dystocia post-epidural analgesia during the early active phase of labor, providing an instant assessment tool for timely intervention and better outcomes.

Keywords: cephalic dystocia, epidural labor analgesia, predictive model, nomogram