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已发表论文
环境空气污染与高血压门诊及急诊就诊的短期关联：基于广西百色DLNM的时间序列分析
Authors Xin M , Liang J, Shang M, Guo R, Deng S, Wei X
Received 10 October 2025
Accepted for publication 15 January 2026
Published 24 January 2026 Volume 2026:19 573334
DOI https://doi.org/10.2147/JMDH.S573334
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 5
Editor who approved publication: Professor Charles V Pollack
Mengdong Xin, Jiancheng Liang, Mingmei Shang, Rui Guo, Shusong Deng, Xiaoxiao Wei
School of Public Health, Youjiang Medical University for Nationalities, Baise, Guangxi, People’s Republic of China
Correspondence: Jiancheng Liang, School of Public Health, Youjiang Medical University of Nationalities, No. 98 Chengxiang Road, Youjiang District, Baise, Guangxi, 533000, People’s Republic of China, Email 2961102720@qq.com
Background: Despite growing evidence that short-term ambient air pollution increases hypertension risk, data from China’s border regions are limited; this study quantifies the association between daily pollutant concentrations and daily emergency and outpatient visits for hypertension in Baise, a southern border city.
Methods: We collected hypertension case data from two tertiary hospitals in Baise City (1 Jan 2020– 30 Dec 2022) and concurrent local air pollutant and meteorological data, and used a distributed lag non-linear model (DLNM) to assess pollutant effects on outpatient and emergency visits, with subgroup analyses by sex, age, and season.
Results: Every 10 μg/m3 increase in PM2.5 (lag06), PM10 (lag06), NO2 (lag06), and every 100 μg/m3 increase in CO (lag04), the risk of hypertension outpatient/emergency department visits increased by 3.2%, 2.8%, 14.8%, and 3.0%, respectively. Exposure–response curves were approximately linear without a clear threshold. There was no statistically significant effect modification by sex or age, whereas associations were stronger in the cold season than in the warm season.
Conclusion: Short-term exposure to pollutants such as PM2.5, PM10, NO2, and CO is significantly associated with increased outpatient and emergency visits for hypertension, exhibiting a lag effect. During cold seasons, sensitivity to environmental pollutants among hypertensive patients markedly increases.
Keywords: air pollutants, DLNM, relative risk, hypertension outpatient and emergency visits
School of Public Health, Youjiang Medical University for Nationalities, Baise, Guangxi, People’s Republic of China
Correspondence: Jiancheng Liang, School of Public Health, Youjiang Medical University of Nationalities, No. 98 Chengxiang Road, Youjiang District, Baise, Guangxi, 533000, People’s Republic of China, Email 2961102720@qq.com
Background: Despite growing evidence that short-term ambient air pollution increases hypertension risk, data from China’s border regions are limited; this study quantifies the association between daily pollutant concentrations and daily emergency and outpatient visits for hypertension in Baise, a southern border city.
Methods: We collected hypertension case data from two tertiary hospitals in Baise City (1 Jan 2020– 30 Dec 2022) and concurrent local air pollutant and meteorological data, and used a distributed lag non-linear model (DLNM) to assess pollutant effects on outpatient and emergency visits, with subgroup analyses by sex, age, and season.
Results: Every 10 μg/m3 increase in PM2.5 (lag06), PM10 (lag06), NO2 (lag06), and every 100 μg/m3 increase in CO (lag04), the risk of hypertension outpatient/emergency department visits increased by 3.2%, 2.8%, 14.8%, and 3.0%, respectively. Exposure–response curves were approximately linear without a clear threshold. There was no statistically significant effect modification by sex or age, whereas associations were stronger in the cold season than in the warm season.
Conclusion: Short-term exposure to pollutants such as PM2.5, PM10, NO2, and CO is significantly associated with increased outpatient and emergency visits for hypertension, exhibiting a lag effect. During cold seasons, sensitivity to environmental pollutants among hypertensive patients markedly increases.
Keywords: air pollutants, DLNM, relative risk, hypertension outpatient and emergency visits