120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
超声引导小口径导管引流复杂分隔性胸腔积液：分隔特征对结局的判别
Received 9 October 2025
Accepted for publication 20 January 2026
Published 24 January 2026 Volume 2026:19 571764
DOI https://doi.org/10.2147/IJGM.S571764
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Reynold Panettieri Jr
Wenqiang Lin,1 Peifen Chen2
1Department of Ultrasound, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, People’s Republic of China; 2Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, People’s Republic of China
Correspondence: Peifen Chen, Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, 57 Changping Road, Shantou, Guangdong Province, 515041, People’s Republic of China, Tel +8613822869774, Email 13822869774@163.com
Purpose: The objective of this study was to identify the sonographic and clinical predictors of drainage procedure failure using small-caliber catheters under ultrasound guidance for complex septated pleural effusions.
Materials and Methods: In this retrospective cohort study, we analyzed 145 consecutive patients who underwent ultrasound-guided small-caliber (6- or 8-Fr) catheter drainage for complex septated pleural effusion at a single tertiary center. Demographic, clinical, and pleural fluid data were collected. Sonographic images were reviewed to classify septation complexity (widespread vs few) and to quantitatively measure septal thickness. Multivariable logistic regression was used to identify independent predictors of drainage failure.
Results: Unsuccessful drainage occurred in 79 patients (54.5%). Widespread septations (72.2% vs 36.4%, P< 0.001) and greater septal thickness (3.3 vs 2.1 mm, P< 0.001) were more common in the unsuccessful group. Multivariable analysis identified widespread septations (adjusted odds ratio [aOR]=2.94, P=0.033) and septal thickness (aOR=3.39 per mm, P< 0.001) as independent predictors of failure. The optimal cut-off for septal thickness was > 2.4 mm (sensitivity 82.3%, specificity 69.7%). An alternative cut-off of > 1.8 mm provided high sensitivity (93.7%) and a negative likelihood ratio (LR−) of 0.1 for ruling out failure.
Conclusion: Quantitative sonographic assessment of septation complexity and thickness independently predicts small-caliber catheter drainage failure in complex septated pleural effusions. Incorporating these parameters into pre-procedural evaluation can aid in risk stratification and guide individualized management, potentially facilitating timely escalation to advanced therapies when indicated.
Keywords: pleural effusion, septation, ultrasonography, drainage, catheterization
1Department of Ultrasound, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, People’s Republic of China; 2Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, People’s Republic of China
Correspondence: Peifen Chen, Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, 57 Changping Road, Shantou, Guangdong Province, 515041, People’s Republic of China, Tel +8613822869774, Email 13822869774@163.com
Purpose: The objective of this study was to identify the sonographic and clinical predictors of drainage procedure failure using small-caliber catheters under ultrasound guidance for complex septated pleural effusions.
Materials and Methods: In this retrospective cohort study, we analyzed 145 consecutive patients who underwent ultrasound-guided small-caliber (6- or 8-Fr) catheter drainage for complex septated pleural effusion at a single tertiary center. Demographic, clinical, and pleural fluid data were collected. Sonographic images were reviewed to classify septation complexity (widespread vs few) and to quantitatively measure septal thickness. Multivariable logistic regression was used to identify independent predictors of drainage failure.
Results: Unsuccessful drainage occurred in 79 patients (54.5%). Widespread septations (72.2% vs 36.4%, P< 0.001) and greater septal thickness (3.3 vs 2.1 mm, P< 0.001) were more common in the unsuccessful group. Multivariable analysis identified widespread septations (adjusted odds ratio [aOR]=2.94, P=0.033) and septal thickness (aOR=3.39 per mm, P< 0.001) as independent predictors of failure. The optimal cut-off for septal thickness was > 2.4 mm (sensitivity 82.3%, specificity 69.7%). An alternative cut-off of > 1.8 mm provided high sensitivity (93.7%) and a negative likelihood ratio (LR−) of 0.1 for ruling out failure.
Conclusion: Quantitative sonographic assessment of septation complexity and thickness independently predicts small-caliber catheter drainage failure in complex septated pleural effusions. Incorporating these parameters into pre-procedural evaluation can aid in risk stratification and guide individualized management, potentially facilitating timely escalation to advanced therapies when indicated.
Keywords: pleural effusion, septation, ultrasonography, drainage, catheterization