120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
基于美国运动医学会建议的运动对1型糖尿病患者血糖管理的影响：随机对照试验系统综述和荟萃分析
Authors Cheng R , Qi Y , He Y , Liu X , Fu X , Zhang F
Received 17 September 2025
Accepted for publication 12 January 2026
Published 28 January 2026 Volume 2026:19 568205
DOI https://doi.org/10.2147/DMSO.S568205
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Melissa Olfert
Rui Cheng,1,* Yangyang Qi,2,* Yuyan He,3 Xiaotong Liu,4 Xiaoxu Fu,5 Fenghua Zhang1
1School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan, People’s Republic of China; 4Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 5TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xiaoxu Fu, TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email fuxiaoxu@cdutcm.edu.cn Fenghua Zhang, School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu, Sichuan, 611137, People’s Republic of China, Email zhangfenghua@cdutcm.edu.cn
Abstract: Exercise is a crucial lifestyle management strategy for individuals with type 1 diabetes (T1DM) to improve overall health, yet its benefits for glycemic control remain controversial. Although clinical trials have designed various exercise regimens, no studies have systematically demonstrated or compared which exercise program yields optimal outcomes for individuals with T1DM. To visually compare and identify a more reasonable exercise program, we used the comprehensive exercise prescription established by the American College of Sports Medicine (ACSM) as a foundation to compare the impact of glycemic management about exercise doses with different compliance to ACSM recommendations. We systematically searched for studies from PubMed, Embase, Web of Science, Cochrane, and OVID. Randomized controlled trials (RCTs) investigating the impact of exercise on glycemic management published between January 2000 and July 11, 2025 were included. The quality of the study was assessed by the Cochrane Collaboration Risk of Bias Tool. Subgroup analyses were performed by categorizing the interventions into high adherence versus low/uncertainty adherence to the exercise prescription developed by ACSM. To compare the results between subgroups, weighted mean difference (WMD) or standardized mean difference (SMD) were adopted, using random or fixed effects models accordingly. Fourteen studies were included in the meta-analysis, with 452 participants. Of which, 7 studies were categorized as high adherence with ACSM and 7 studies were categorized as low or uncertain adherence. Results showed exercise had significant effect on reducing Glycated Hemoglobin (HbA1c) (WMD = − 0.52; 95% CI = [− 0.74, − 0.29]). The WMD for the high adherence group was − 0.74 (95% CI: − 1.04, − 0.44), while for the low or uncertain adherence group was − 0.21 (95% CI: [− 0.56, 0.13]). Exercise programs with high adherence to the ACSM resulted in a markedly greater reduction in HbA1c compared to those with low adherence (p = 0.02). Data on triglyceride levels also showed greater improvements in the high adherence group. These findings collectively indicated that the ACSM prescription serves as an effective exercise guideline for individuals with type 1 diabetes.
Keywords: type 1 diabetes mellitus, exercise dose, ACSM recommendations, blood glucose, HbA1c
1School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan, People’s Republic of China; 4Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 5TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xiaoxu Fu, TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email fuxiaoxu@cdutcm.edu.cn Fenghua Zhang, School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu, Sichuan, 611137, People’s Republic of China, Email zhangfenghua@cdutcm.edu.cn
Abstract: Exercise is a crucial lifestyle management strategy for individuals with type 1 diabetes (T1DM) to improve overall health, yet its benefits for glycemic control remain controversial. Although clinical trials have designed various exercise regimens, no studies have systematically demonstrated or compared which exercise program yields optimal outcomes for individuals with T1DM. To visually compare and identify a more reasonable exercise program, we used the comprehensive exercise prescription established by the American College of Sports Medicine (ACSM) as a foundation to compare the impact of glycemic management about exercise doses with different compliance to ACSM recommendations. We systematically searched for studies from PubMed, Embase, Web of Science, Cochrane, and OVID. Randomized controlled trials (RCTs) investigating the impact of exercise on glycemic management published between January 2000 and July 11, 2025 were included. The quality of the study was assessed by the Cochrane Collaboration Risk of Bias Tool. Subgroup analyses were performed by categorizing the interventions into high adherence versus low/uncertainty adherence to the exercise prescription developed by ACSM. To compare the results between subgroups, weighted mean difference (WMD) or standardized mean difference (SMD) were adopted, using random or fixed effects models accordingly. Fourteen studies were included in the meta-analysis, with 452 participants. Of which, 7 studies were categorized as high adherence with ACSM and 7 studies were categorized as low or uncertain adherence. Results showed exercise had significant effect on reducing Glycated Hemoglobin (HbA1c) (WMD = − 0.52; 95% CI = [− 0.74, − 0.29]). The WMD for the high adherence group was − 0.74 (95% CI: − 1.04, − 0.44), while for the low or uncertain adherence group was − 0.21 (95% CI: [− 0.56, 0.13]). Exercise programs with high adherence to the ACSM resulted in a markedly greater reduction in HbA1c compared to those with low adherence (p = 0.02). Data on triglyceride levels also showed greater improvements in the high adherence group. These findings collectively indicated that the ACSM prescription serves as an effective exercise guideline for individuals with type 1 diabetes.
Keywords: type 1 diabetes mellitus, exercise dose, ACSM recommendations, blood glucose, HbA1c