120017
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.6 Breast Cancer (Dove Med Press)
- 4.3 Clin Epidemiol
- 2.6 Cancer Manag Res
- 3.2 Infect Drug Resist
- 4.1 Clin Interv Aging
- 6.1 Drug Des Dev Ther
- 4.1 Int J Chronic Obstr
- 8.7 Int J Nanomed
- 2.5 Int J Women's Health
- 3.2 Neuropsych Dis Treat
- 2.4 OncoTargets Ther
- 2.6 Patient Prefer Adher
- 2.6 Ther Clin Risk Manag
- 3.1 J Pain Res
- 3.5 Diabet Metab Synd Ob
- 4.5 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 2.4 Pharmgenomics Pers Med
- 2.6 Risk Manag Healthc Policy
- 4.6 J Inflamm Res
- 2.3 Int J Gen Med
- 3.9 J Hepatocell Carcinoma
- 3.3 J Asthma Allergy
- 2.5 Clin Cosmet Investig Dermatol
- 3.0 J Multidiscip Healthc
已发表论文
改善肥胖男性精液质量的治疗选择：范围综述
Authors Wang H , Chang H, Zhao Y, Wu S, Luo D, Sun D
Received 17 November 2025
Accepted for publication 22 January 2026
Published 29 January 2026 Volume 2026:19 582182
DOI https://doi.org/10.2147/JMDH.S582182
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Pavani Rangachari
Hao Wang,1 Hongyuan Chang,1 Yongqing Zhao,2 Shuang Wu,2 Dicheng Luo,2 Di Sun3
1Department of Andrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 2Graduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Department of Andrology, Chongqing University Three Gorges Hospital, Chongqing, People’s Republic of China
Correspondence: Di Sun, Department of Andrology, Chongqing University Three Gorges Hospital, Chongqing, People’s Republic of China, Email sundi123dc@126.com
Abstract: Obesity is a significant factor affecting male fertility. Infertility in obese men often accompanies with metabolic dysfunction and differs from idiopathic male infertility (MI) in treatment approaches. This scoping review summarizes published treatment options for affecting the semen quality in obese men. A comprehensive literature search strategy was conducted via PubMed, Web of Science, and China National Knowledge Infrastructure. Inclusion criteria encompassed clinical research articles focusing on obese men. Finally, 28 eligible clinical studies were included. Treatment options for improving the semen quality in obese male encompass bariatric surgery, lifestyle modifications (eg, exercise training, dietary adjustments), glucagon-like peptide-1 receptor agonists, selective estrogen receptor modulators, testosterone, aromatase inhibitors, nutritional supplements, traditional Chinese medicine, etc. Patients may benefit from combination therapies. Future directions should explore more effective treatment approaches, prioritize the overall health of obese infertile men, evaluate the impact of interventions on offspring and develop the standard treatment guidelines based on the high-level clinical evidence.
Keywords: semen quality, obese men, treatment, bariatric surgery, lifestyle
1Department of Andrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 2Graduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Department of Andrology, Chongqing University Three Gorges Hospital, Chongqing, People’s Republic of China
Correspondence: Di Sun, Department of Andrology, Chongqing University Three Gorges Hospital, Chongqing, People’s Republic of China, Email sundi123dc@126.com
Abstract: Obesity is a significant factor affecting male fertility. Infertility in obese men often accompanies with metabolic dysfunction and differs from idiopathic male infertility (MI) in treatment approaches. This scoping review summarizes published treatment options for affecting the semen quality in obese men. A comprehensive literature search strategy was conducted via PubMed, Web of Science, and China National Knowledge Infrastructure. Inclusion criteria encompassed clinical research articles focusing on obese men. Finally, 28 eligible clinical studies were included. Treatment options for improving the semen quality in obese male encompass bariatric surgery, lifestyle modifications (eg, exercise training, dietary adjustments), glucagon-like peptide-1 receptor agonists, selective estrogen receptor modulators, testosterone, aromatase inhibitors, nutritional supplements, traditional Chinese medicine, etc. Patients may benefit from combination therapies. Future directions should explore more effective treatment approaches, prioritize the overall health of obese infertile men, evaluate the impact of interventions on offspring and develop the standard treatment guidelines based on the high-level clinical evidence.
Keywords: semen quality, obese men, treatment, bariatric surgery, lifestyle