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已发表论文
围手术期音乐疗法改善50—70岁全膝关节置换术患者疼痛管理和睡眠质量：一项随机对照试验
Authors Yang L, Liu X, Fu X, Qing Z, Li Y, Yang G
Received 14 August 2025
Accepted for publication 14 January 2026
Published 21 January 2026 Volume 2026:19 560546
DOI https://doi.org/10.2147/JPR.S560546
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jinlei Li
Lin Yang,1,* Xu Liu,2,* Xiaoli Fu,3 Zhong Qing,4 Yusheng Li,2 Guang Yang1
1Department of Anesthesiology, Honghui Hospital, Xi'an Jiaotong University, Xi'an, People's Republic of China; 2Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Anesthesiology, Northwest Women’s and Children’s Hospital, Xi’an, People’s Republic of China; 4Department of Orthopedics, Honghui Hospital, Xi’an, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Guang Yang, Email 850303584@qq.com
Purpose: Music therapy (MT) has recently shown its value in alleviating pain in surgical patients. To explore its perioperative analgesic effects in patients undergoing total knee arthroplasty (TKA) under general anesthesia, we conducted a randomized single-blind clinical trial.
Patients and Methods: Eighty-six patients aged 50– 70 years (ASA II–III) undergoing TKA at Honghui Hospital were randomly assigned to either a music group or a control group. The music group listened to music via headphones from 10 minutes before anesthesia induction until awakening after surgery. The control group wore headphones without music for the same period. All patients received standardized general anesthesia with BIS values maintained between 40 and 60. Postoperatively, a patient-controlled analgesia (PCA) pump was used. Outcome measures included Visual Analogue Scale (VAS) pain scores, analgesic dosage, PCA usage, Nausea VAS (NVAS), Pittsburgh Sleep Quality Index (PSQI), and satisfaction with analgesia at 1h, 2h, 3h, 12h, 24h, and 48h after surgery.
Results: The music group showed significantly fewer PCA presses at 1h and 3h post-operation (p < 0.05), with no significant differences at later time points. Sleep quality and analgesia satisfaction on the first postoperative night were also significantly better in the music group (p < 0.05). No significant differences were found in VAS, NVAS, or analgesic dosage at most time points.
Conclusion: Perioperative music therapy can effectively support PCA for a specific postoperative period, alleviating early postoperative pain, enhancing sleep, and improving patient satisfaction with analgesia in TKA patients.
Keywords: music therapy, self-controlled analgesia, total knee arthroplasty, pain manage
1Department of Anesthesiology, Honghui Hospital, Xi'an Jiaotong University, Xi'an, People's Republic of China; 2Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Anesthesiology, Northwest Women’s and Children’s Hospital, Xi’an, People’s Republic of China; 4Department of Orthopedics, Honghui Hospital, Xi’an, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Guang Yang, Email 850303584@qq.com
Purpose: Music therapy (MT) has recently shown its value in alleviating pain in surgical patients. To explore its perioperative analgesic effects in patients undergoing total knee arthroplasty (TKA) under general anesthesia, we conducted a randomized single-blind clinical trial.
Patients and Methods: Eighty-six patients aged 50– 70 years (ASA II–III) undergoing TKA at Honghui Hospital were randomly assigned to either a music group or a control group. The music group listened to music via headphones from 10 minutes before anesthesia induction until awakening after surgery. The control group wore headphones without music for the same period. All patients received standardized general anesthesia with BIS values maintained between 40 and 60. Postoperatively, a patient-controlled analgesia (PCA) pump was used. Outcome measures included Visual Analogue Scale (VAS) pain scores, analgesic dosage, PCA usage, Nausea VAS (NVAS), Pittsburgh Sleep Quality Index (PSQI), and satisfaction with analgesia at 1h, 2h, 3h, 12h, 24h, and 48h after surgery.
Results: The music group showed significantly fewer PCA presses at 1h and 3h post-operation (p < 0.05), with no significant differences at later time points. Sleep quality and analgesia satisfaction on the first postoperative night were also significantly better in the music group (p < 0.05). No significant differences were found in VAS, NVAS, or analgesic dosage at most time points.
Conclusion: Perioperative music therapy can effectively support PCA for a specific postoperative period, alleviating early postoperative pain, enhancing sleep, and improving patient satisfaction with analgesia in TKA patients.
Keywords: music therapy, self-controlled analgesia, total knee arthroplasty, pain manage