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已发表论文
洗衣液中苯扎氯铵诱发的系统性接触性皮炎：一例初诊误诊为湿疹的病例
Received 28 October 2025
Accepted for publication 15 January 2026
Published 22 January 2026 Volume 2026:19 577154
DOI https://doi.org/10.2147/CCID.S577154
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Michela Starace
Man Yu,1 Fanlin Meng,2 Shue Tian3
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Emergency Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 3Department of Dermatology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, 618000, People’s Republic of China
Correspondence: Shue Tian, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, People’s Republic of China, Tel +86-028-87769233, Email tianshue2021@163.com
Abstract: This case shows that benzalkonium chloride is an important sensitizer for contact dermatitis.The patient did not respond to conventional eczema treatment. Pathological examination and detailed history-taking revealed that benzalkonium chloride in the detergent was the causative factor. After avoiding exposure to this allergen, the condition improved, emphasizing the need to consider contact dermatitis in patients with refractory eczema.
Keywords: contact dermatitis, benzalkonium chloride, detergent, Eczematous rash
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Emergency Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 3Department of Dermatology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, 618000, People’s Republic of China
Correspondence: Shue Tian, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, People’s Republic of China, Tel +86-028-87769233, Email tianshue2021@163.com
Abstract: This case shows that benzalkonium chloride is an important sensitizer for contact dermatitis.The patient did not respond to conventional eczema treatment. Pathological examination and detailed history-taking revealed that benzalkonium chloride in the detergent was the causative factor. After avoiding exposure to this allergen, the condition improved, emphasizing the need to consider contact dermatitis in patients with refractory eczema.
Keywords: contact dermatitis, benzalkonium chloride, detergent, Eczematous rash