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已发表论文
成人开放性创面患者创面操作性疼痛的预防和管理：最新临床证据整合
Authors Yao H, Yang F, Ye X, Yang Y, Li J
Received 25 August 2025
Accepted for publication 25 December 2025
Published 12 January 2026 Volume 2026:19 563157
DOI https://doi.org/10.2147/JPR.S563157
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Gillian Chumbley
Honglin Yao,1 Fan Yang,1 Xianghong Ye,1 Yang Yang,1 Jiaqi Li2
1Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 2Operation Room, Hainan General Hospital, Haikou, People’s Republic of China
Correspondence: Jiaqi Li, Email ljqnju123@163.com
Purpose: To retrieve, evaluate, and integrate the best available evidence on prevention and management of wound procedural pain management in patients with open wounds, providing evidence-based guidance for clinical practice.
Patients and Methods: Following the “ 6S” pyramid model, we systematically searched guideline websites, professional association websites, and databases for guidelines, clinical decision aids, expert consensus statements, evidence summaries, recommended practices, and systematic reviews related to wound procedural pain management in patients with open wounds. The search period was from the establishment of the database to July 2025. Two researchers independently conducted literature quality assessment, evidence extraction, and synthesis.
Results: A total of 23 documents were included: 5 guidelines, 1 expert consensus, 3 recommended practices, 3 clinical decisions, 6 evidence summaries, and 5 systematic reviews. Thirty-two best evidence statements were summarized across six aspects: pain assessment and documentation, education and training, dressing selection and replacement, wound cleansing, debridement, and negative pressure therapy, pharmacological intervention strategies, and non-pharmacological intervention strategies.
Conclusion: This study reviews the best available evidence on managing procedural pain in open wounds. It offers guidance on the principles of pain management, standardization of procedural techniques, and the timely application of analgesic, emphasizing the importance of pain awareness. The research serves as a reference for developing specialized pain management protocols to improve wound care quality.
Keywords: wound procedural pain, open wounds, evidence-based nursing, clinical evidence
1Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 2Operation Room, Hainan General Hospital, Haikou, People’s Republic of China
Correspondence: Jiaqi Li, Email ljqnju123@163.com
Purpose: To retrieve, evaluate, and integrate the best available evidence on prevention and management of wound procedural pain management in patients with open wounds, providing evidence-based guidance for clinical practice.
Patients and Methods: Following the “ 6S” pyramid model, we systematically searched guideline websites, professional association websites, and databases for guidelines, clinical decision aids, expert consensus statements, evidence summaries, recommended practices, and systematic reviews related to wound procedural pain management in patients with open wounds. The search period was from the establishment of the database to July 2025. Two researchers independently conducted literature quality assessment, evidence extraction, and synthesis.
Results: A total of 23 documents were included: 5 guidelines, 1 expert consensus, 3 recommended practices, 3 clinical decisions, 6 evidence summaries, and 5 systematic reviews. Thirty-two best evidence statements were summarized across six aspects: pain assessment and documentation, education and training, dressing selection and replacement, wound cleansing, debridement, and negative pressure therapy, pharmacological intervention strategies, and non-pharmacological intervention strategies.
Conclusion: This study reviews the best available evidence on managing procedural pain in open wounds. It offers guidance on the principles of pain management, standardization of procedural techniques, and the timely application of analgesic, emphasizing the importance of pain awareness. The research serves as a reference for developing specialized pain management protocols to improve wound care quality.
Keywords: wound procedural pain, open wounds, evidence-based nursing, clinical evidence