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已发表论文
中重度痤疮患者对口服药物治疗的知识、态度和实践：一项结构方程模型分析
Authors Wang J, Bai D, Yao X, Song X, Yang X, Yuan Y
Received 14 August 2025
Accepted for publication 18 December 2025
Published 12 January 2026 Volume 2026:19 554435
DOI https://doi.org/10.2147/CCID.S554435
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Prof. Dr. Rungsima Wanitphakdeedecha
Jiejun Wang,1 Dou Bai,1 Xiaoyuan Yao,1 Xinze Song,1 Xufei Yang,1 Yanli Yuan2
1Department of Dermatology, Dingxi People’s Hospital, Dingxi, Gansu, 743000, People’s Republic of China; 2Department of Dermatology, Jiuquan People’s Hospital, Jiuquan, Gansu, 735000, People’s Republic of China
Correspondence: Yanli Yuan, Department of Dermatology, Jiuquan People’s Hospital, Jiuquan, Gansu, 735000, People’s Republic of China, Tel +86-15209378030, Email 710852894@qq.com
Purpose: Acne affects up to 9% of the global population, with rising prevalence among Chinese urban youth, leading to significant physical and psychological impacts.
Patients and Methods: A cross-sectional study was conducted at the Dingxi People’s Hospital. Data on the demographics and knowledge, attitudes, and practices (KAP) of patients with moderate to severe acne were collected through questionnaire distribution.
Results: A total of 561 patients were included in the study, of them 58.65% females, The majority of participants believed that they have sufficient knowledge of routine acne management and 72.72% reported that they are satisfied with the current effectiveness of medication treatment. However, predominant answer for all questions regarding the oral treatment of acne (40.29%-58.82%) or combination therapy (23.89%-41.53%) was “unsure”. Knowledge score was positively correlated with attitude score (p < 0.001) and practice score (p < 0.001), and higher knowledge scale scores were associated with higher practice scores according to logistic regression analysis (p = 0.002). According to the Structural equation modelling knowledge influenced practice directly and indirectly.
Conclusion: This study found that patients with moderate to severe acne in China might overestimate their knowledge of oral medication therapy and ability to manage acne. Targeted healthcare education is needed to address the identified gaps, ultimately optimizing acne management strategies and enhancing patient outcomes.
Keywords: acne vulgaris, medication adherence, psychological well-being, health knowledge, attitudes, practice, surveys and questionnaires
1Department of Dermatology, Dingxi People’s Hospital, Dingxi, Gansu, 743000, People’s Republic of China; 2Department of Dermatology, Jiuquan People’s Hospital, Jiuquan, Gansu, 735000, People’s Republic of China
Correspondence: Yanli Yuan, Department of Dermatology, Jiuquan People’s Hospital, Jiuquan, Gansu, 735000, People’s Republic of China, Tel +86-15209378030, Email 710852894@qq.com
Purpose: Acne affects up to 9% of the global population, with rising prevalence among Chinese urban youth, leading to significant physical and psychological impacts.
Patients and Methods: A cross-sectional study was conducted at the Dingxi People’s Hospital. Data on the demographics and knowledge, attitudes, and practices (KAP) of patients with moderate to severe acne were collected through questionnaire distribution.
Results: A total of 561 patients were included in the study, of them 58.65% females, The majority of participants believed that they have sufficient knowledge of routine acne management and 72.72% reported that they are satisfied with the current effectiveness of medication treatment. However, predominant answer for all questions regarding the oral treatment of acne (40.29%-58.82%) or combination therapy (23.89%-41.53%) was “unsure”. Knowledge score was positively correlated with attitude score (p < 0.001) and practice score (p < 0.001), and higher knowledge scale scores were associated with higher practice scores according to logistic regression analysis (p = 0.002). According to the Structural equation modelling knowledge influenced practice directly and indirectly.
Conclusion: This study found that patients with moderate to severe acne in China might overestimate their knowledge of oral medication therapy and ability to manage acne. Targeted healthcare education is needed to address the identified gaps, ultimately optimizing acne management strategies and enhancing patient outcomes.
Keywords: acne vulgaris, medication adherence, psychological well-being, health knowledge, attitudes, practice, surveys and questionnaires