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已发表论文
斜外侧腰椎椎间融合术与后路腰椎椎间融合术治疗重度腰椎管狭窄症的中长期影像学和临床结局：一项回顾性比较研究
Authors Hu J, Xu H, Ma X, Yang X, Zhang S
Received 4 August 2025
Accepted for publication 30 December 2025
Published 13 January 2026 Volume 2026:19 552131
DOI https://doi.org/10.2147/JPR.S552131
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Michael Überall
Jianwei Hu,1 Hui Xu,2 Xixi Ma,3 Xiaoli Yang,3 Shuai Zhang3
1Trauma Ward, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, Fujian Province, People’s Republic of China; 2Orthopedics Department, Fuzhou Xiaozhi’an TCM Surgery Hospital, Fuzhou, Fujian Province, People’s Republic of China; 3Joint Surgery Ward, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, Fujian Province, People’s Republic of China
Correspondence: Shuai Zhang, Email 773188885@qq.com
Purpose: To explore and compare the clinical efficacy and radiological changes of oblique lateral interbody fusion (OLIF) and posterior lumbar interbody fusion (PLIF) in patients with severe lumbar spinal stenosis (LSS).
Patients and Methods: We retrospectively collected data from 34 patients with severe LSS (Schizas grade C or D) who underwent either OLIF or PLIF at our institution between June 2014 and June 2020. Imaging evaluation included the cross-sectional area (CSA) of the spinal canal and ligamentum flavum on MRI. Clinical evaluation included Visual Analogue Scale (VAS) scores and Oswestry Disability Index (ODI). Statistical analysis was performed using independent sample t-tests and analysis of variance for repeated measures.
Results: The cross-sectional area of the spinal canal in the OLIF group was gradually expanded from 47.6 ± 16.5 mm2 preoperatively to 67.0 ± 17.8 mm2 at 3 weeks and further to 97.5 ± 22.3 mm2 at 1 year (P < 0.05), while the area of ligamentum flavum was decreased from 119.9 ± 49.7 mm2 to 107.0 ± 38.9 mm2 and to 87.8 ± 25.3 mm2, respectively (P < 0.05). At 3 weeks after the operation, the improvement of VAS score (Low back: 1.3 vs 3.8; Leg: 1.6 vs 3.6) and ODI (12.24 vs 35.21) of low back and leg pain in the PLIF group was better than that in the OLIF group (P < 0.05). There was no significant difference in VAS score and ODI between the two groups 1 year after operation (P > 0.05).
Conclusion: OLIF technology provides significant mid-term (1-year) spinal canal dilatation and clinical improvement in severe LSS, achieving outcomes comparable to PLIF. Therefore, OLIF can be considered a viable and effective surgical option for severe LSS.
Keywords: oblique lateral interbody fusion, indirect decompression, lumbar spinal stenosis, MRI, clinical features
1Trauma Ward, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, Fujian Province, People’s Republic of China; 2Orthopedics Department, Fuzhou Xiaozhi’an TCM Surgery Hospital, Fuzhou, Fujian Province, People’s Republic of China; 3Joint Surgery Ward, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, Fujian Province, People’s Republic of China
Correspondence: Shuai Zhang, Email 773188885@qq.com
Purpose: To explore and compare the clinical efficacy and radiological changes of oblique lateral interbody fusion (OLIF) and posterior lumbar interbody fusion (PLIF) in patients with severe lumbar spinal stenosis (LSS).
Patients and Methods: We retrospectively collected data from 34 patients with severe LSS (Schizas grade C or D) who underwent either OLIF or PLIF at our institution between June 2014 and June 2020. Imaging evaluation included the cross-sectional area (CSA) of the spinal canal and ligamentum flavum on MRI. Clinical evaluation included Visual Analogue Scale (VAS) scores and Oswestry Disability Index (ODI). Statistical analysis was performed using independent sample t-tests and analysis of variance for repeated measures.
Results: The cross-sectional area of the spinal canal in the OLIF group was gradually expanded from 47.6 ± 16.5 mm2 preoperatively to 67.0 ± 17.8 mm2 at 3 weeks and further to 97.5 ± 22.3 mm2 at 1 year (P < 0.05), while the area of ligamentum flavum was decreased from 119.9 ± 49.7 mm2 to 107.0 ± 38.9 mm2 and to 87.8 ± 25.3 mm2, respectively (P < 0.05). At 3 weeks after the operation, the improvement of VAS score (Low back: 1.3 vs 3.8; Leg: 1.6 vs 3.6) and ODI (12.24 vs 35.21) of low back and leg pain in the PLIF group was better than that in the OLIF group (P < 0.05). There was no significant difference in VAS score and ODI between the two groups 1 year after operation (P > 0.05).
Conclusion: OLIF technology provides significant mid-term (1-year) spinal canal dilatation and clinical improvement in severe LSS, achieving outcomes comparable to PLIF. Therefore, OLIF can be considered a viable and effective surgical option for severe LSS.
Keywords: oblique lateral interbody fusion, indirect decompression, lumbar spinal stenosis, MRI, clinical features