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已发表论文
颞下颌关节紊乱病患者的心理社会、行为和生活质量特征：年轻患者与成熟患者的比较探索
Authors Yap AU, Zheng Y , Yang M , Liu T, Li Y, Hu T , Wang J , Xiong X
Received 4 June 2025
Accepted for publication 17 December 2025
Published 13 January 2026 Volume 2026:19 540623
DOI https://doi.org/10.2147/JPR.S540623
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 4
Editor who approved publication: Dr Rune Häckert Christensen
Adrian Ujin Yap,1– 3,* Yunhao Zheng,1,4,* Ming Yang,4 Tiqian Liu,4 Yijun Li,4 Ting Hu,5 Jun Wang,4 Xin Xiong1,4
1West China School of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Division of Dentistry, Ng Teng Fong General Hospital and Faculty of Dentistry, National University Health System, Singapore; 3National Dental Research Institute Singapore, National Dental Centre Singapore and Duke-NUS Medical School, Singapore Health Services, Singapore; 4State Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 5No.1 Orthopedics Hospital of Chengdu, Chengdu, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xin Xiong, State Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, West China School of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, People’s Republic of China, Tel +86-028-85501425, Email drxiongxin@scu.edu.cn
Objective: Despite its global adoption and translation, studies reporting age-stratified Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I and II findings remain scarce. This study aimed to 1) compare TMD diagnostic categories, psychosocial/behavioral profiles, and Oral Health-related Quality of Life (OHRQoL) across age groups, 2) explore correlations between psychosocial/behavioral variables and OHRQoL, and 3) identify factors associated with low OHRQoL among Chinese adult TMD patients.
Methods: A total of 798 participants were recruited from a dental hospital and categorized into: young (YA: 18– 44), mature patients (MA: 45– 64), and old patients (OA: ≥ 65 years). They were assessed using DC/TMD Axis I procedures and Axis II measures for depression, anxiety, oral behaviors, and jaw function. OHRQoL was evaluated with the Oral Health Impact Profile for TMDs. Statistical analyses were performed using Chi-square/non-parametric tests and logistic regression (α = 0.05).
Results: The final sample included 798 participants (79.6% women), of whom 88.0%, 11.0%, and 1.0% were YA, MA, and OA, respectively. Significant differences in education level (YA > MA/OA), intra-articular TMDs (YA > MA), jaw overuse behaviors (YA > MA/OA), jaw functional limitation (MA > YA), and OHRQoL (MA > YA) were observed. Moderate correlations were noted between OHRQoL and depression, anxiety, and jaw functional limitation (rs = 0.50– 0.61) across all groups, as well as between jaw overuse behavior and both depression and anxiety (rs = 0.43– 0.45) for the MA group.
Conclusion: Mature (MA/OA) TMD patients exhibited reduced oral behaviors but experienced greater jaw function and OHRQoL impairments. TMD pain doubled the likelihood of low OHRQoL.
Clinical Relevance: Age-related differences in physical diagnosis, oral behaviors, jaw function, and OHRQoL are evident among TMD patients. Older individuals exhibit fewer oral behaviors but face greater jaw limitations and poorer OHRQoL, highlighting the importance of tailored management across age group.
Keywords: temporomandibular disorders, age, psychosocial, oral behaviors, oral health-related quality of life
1West China School of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 2Division of Dentistry, Ng Teng Fong General Hospital and Faculty of Dentistry, National University Health System, Singapore; 3National Dental Research Institute Singapore, National Dental Centre Singapore and Duke-NUS Medical School, Singapore Health Services, Singapore; 4State Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People’s Republic of China; 5No.1 Orthopedics Hospital of Chengdu, Chengdu, Sichuan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xin Xiong, State Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, West China School of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, People’s Republic of China, Tel +86-028-85501425, Email drxiongxin@scu.edu.cn
Objective: Despite its global adoption and translation, studies reporting age-stratified Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I and II findings remain scarce. This study aimed to 1) compare TMD diagnostic categories, psychosocial/behavioral profiles, and Oral Health-related Quality of Life (OHRQoL) across age groups, 2) explore correlations between psychosocial/behavioral variables and OHRQoL, and 3) identify factors associated with low OHRQoL among Chinese adult TMD patients.
Methods: A total of 798 participants were recruited from a dental hospital and categorized into: young (YA: 18– 44), mature patients (MA: 45– 64), and old patients (OA: ≥ 65 years). They were assessed using DC/TMD Axis I procedures and Axis II measures for depression, anxiety, oral behaviors, and jaw function. OHRQoL was evaluated with the Oral Health Impact Profile for TMDs. Statistical analyses were performed using Chi-square/non-parametric tests and logistic regression (α = 0.05).
Results: The final sample included 798 participants (79.6% women), of whom 88.0%, 11.0%, and 1.0% were YA, MA, and OA, respectively. Significant differences in education level (YA > MA/OA), intra-articular TMDs (YA > MA), jaw overuse behaviors (YA > MA/OA), jaw functional limitation (MA > YA), and OHRQoL (MA > YA) were observed. Moderate correlations were noted between OHRQoL and depression, anxiety, and jaw functional limitation (rs = 0.50– 0.61) across all groups, as well as between jaw overuse behavior and both depression and anxiety (rs = 0.43– 0.45) for the MA group.
Conclusion: Mature (MA/OA) TMD patients exhibited reduced oral behaviors but experienced greater jaw function and OHRQoL impairments. TMD pain doubled the likelihood of low OHRQoL.
Clinical Relevance: Age-related differences in physical diagnosis, oral behaviors, jaw function, and OHRQoL are evident among TMD patients. Older individuals exhibit fewer oral behaviors but face greater jaw limitations and poorer OHRQoL, highlighting the importance of tailored management across age group.
Keywords: temporomandibular disorders, age, psychosocial, oral behaviors, oral health-related quality of life