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已发表论文
单侧经皮弯角椎体后凸成形术与双侧经皮椎体后凸成形术治疗单节段骨质疏松性椎体压缩骨折的回顾性比较研究
Authors Xie C , Tang H, Liu G, Jin X, Wen SH, Li Y, Chen M, Zhang X
Received 11 June 2025
Accepted for publication 14 December 2025
Published 28 December 2025 Volume 2025:18 Pages 7199—7212
DOI https://doi.org/10.2147/JPR.S544051
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Andrea Tinnirello
Chuanjiang Xie, Hong Tang, Gang Liu, Xinglin Jin, Shao hua Wen, Yongqiang Li, Ming Chen, Xintai Zhang
Department of Orthopedics, Nanan District People’s Hospital, Chongqing, People’s Republic of China
Correspondence: Xintai Zhang, Department of Orthopedics, Nanan District People’s Hospital, No. 34, Jiangnan Avenue, Nanan District, Chongqing, 400060, People’s Republic of China, Email 420984695@qq.com
Objective: This study compared unilateral percutaneous curved kyphoplasty (PCK) and bilateral percutaneous kyphoplasty (PKP) for treating single-level osteoporotic vertebral compression fractures (OVCFs).
Methods: A retrospective analysis was conducted on patients with single-level OVCF treated with either unilateral PCK or bilateral PKP between September 2023 and December 2024. Clinical and radiographic evaluations were performed preoperatively and postoperatively at 1 day, 1, 3, 6 months, and at the latest available follow-up. The final data analysis was conducted in July 2025. Given the study period, the latest follow-up time varied among patients, ranging from 6 to 12 months. The median follow-up time for the entire cohort was 12 months. Parameters assessed included operative time, blood loss, fluoroscopy frequency, cement volume, cement leakage, visual analogue scale (VAS) scores, Oswestry Disability Index (ODI), vertebral height restoration, Cobb angle correction, and complication rates.
Results: The PCK group showed superior intraoperative outcomes, including shorter operative time (37.44 ± 6.52 min vs 44.56 ± 7.74 min), reduced blood loss (8.78 ± 2.91 mL vs 12.81 ± 2.51 mL), fewer fluoroscopic exposures (15.37 ± 2.09 vs 21.79 ± 2.46), and lower cement volume (4.62 ± 0.60 mL vs 5.14 ± 0.69 mL). Cement leakage was significantly less frequent with PCK (4.9% vs 18.8%). Both techniques achieved equivalent long-term clinical results, with no significant differences in VAS scores, ODI scores, vertebral height maintenance, Cobb angle correction, or refracture rates at final follow-up. No major complications occurred in either group.
Conclusion: In this retrospective cohort, with a median follow-up of 12 months, unilateral PCK achieved clinical outcomes comparable to those of bilateral PKP. Furthermore, PCK was associated with superior intraoperative efficiency and reduced radiation exposure. These results suggest that PCK may be a viable and advantageous surgical alternative; however, these findings warrant validation in future randomised controlled trials.
Keywords: unilateral percutaneous curved kyphoplasty, bilateral percutaneous kyphoplasty, osteoporotic vertebral compression fracture
Department of Orthopedics, Nanan District People’s Hospital, Chongqing, People’s Republic of China
Correspondence: Xintai Zhang, Department of Orthopedics, Nanan District People’s Hospital, No. 34, Jiangnan Avenue, Nanan District, Chongqing, 400060, People’s Republic of China, Email 420984695@qq.com
Objective: This study compared unilateral percutaneous curved kyphoplasty (PCK) and bilateral percutaneous kyphoplasty (PKP) for treating single-level osteoporotic vertebral compression fractures (OVCFs).
Methods: A retrospective analysis was conducted on patients with single-level OVCF treated with either unilateral PCK or bilateral PKP between September 2023 and December 2024. Clinical and radiographic evaluations were performed preoperatively and postoperatively at 1 day, 1, 3, 6 months, and at the latest available follow-up. The final data analysis was conducted in July 2025. Given the study period, the latest follow-up time varied among patients, ranging from 6 to 12 months. The median follow-up time for the entire cohort was 12 months. Parameters assessed included operative time, blood loss, fluoroscopy frequency, cement volume, cement leakage, visual analogue scale (VAS) scores, Oswestry Disability Index (ODI), vertebral height restoration, Cobb angle correction, and complication rates.
Results: The PCK group showed superior intraoperative outcomes, including shorter operative time (37.44 ± 6.52 min vs 44.56 ± 7.74 min), reduced blood loss (8.78 ± 2.91 mL vs 12.81 ± 2.51 mL), fewer fluoroscopic exposures (15.37 ± 2.09 vs 21.79 ± 2.46), and lower cement volume (4.62 ± 0.60 mL vs 5.14 ± 0.69 mL). Cement leakage was significantly less frequent with PCK (4.9% vs 18.8%). Both techniques achieved equivalent long-term clinical results, with no significant differences in VAS scores, ODI scores, vertebral height maintenance, Cobb angle correction, or refracture rates at final follow-up. No major complications occurred in either group.
Conclusion: In this retrospective cohort, with a median follow-up of 12 months, unilateral PCK achieved clinical outcomes comparable to those of bilateral PKP. Furthermore, PCK was associated with superior intraoperative efficiency and reduced radiation exposure. These results suggest that PCK may be a viable and advantageous surgical alternative; however, these findings warrant validation in future randomised controlled trials.
Keywords: unilateral percutaneous curved kyphoplasty, bilateral percutaneous kyphoplasty, osteoporotic vertebral compression fracture