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已发表论文
内镜辅助下颈椎前路单节段椎间盘切除融合术治疗颈椎病脊髓型的临床疗效：一项回顾性倾向评分匹配研究
Authors Li T, Ma J, Zhang H, Jiang Q, Ding Y
Received 17 September 2025
Accepted for publication 10 December 2025
Published 22 December 2025 Volume 2025:21 Pages 1795—1805
DOI https://doi.org/10.2147/TCRM.S568319
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Professor Garry Walsh
Tusheng Li,* Jingbo Ma,* Hanshuo Zhang, Qiang Jiang, Yu Ding
Orthopedics of TCM Senior Department, the Sixth Medical Center of PLA General Hospital, Beijing, People’ s Republic of China
*These authors contributed equally to this work
Correspondence: Yu Ding, Orthopedics of TCM Senior Department, the Sixth Medical Center of PLA General Hospital, Beijing, People’ s Republic of China, Email cosmos_dingyu@163.com
Purpose: Endoscopy-assisted anterior cervical discectomy and fusion (EA-ACDF), which integrates the advantages of conventional ACDF and spinal endoscopy, is an innovative technique for treating cervical spondylotic myelopathy (CSM). We compared the clinical efficacy of EA-ACDF and ACDF for treating patients with single-segment CSM.
Methods: One-hundred and thirty-six CSM patients were retrospectively included from January 2021 to September 2023, of whom 61 underwent EA-ACDF and 75 underwent ACDF. Propensity score matching (PSM) was conducted to adjust for imbalances in covariates between groups. Then, clinical and imaging outcomes, perioperative data, and complications were compared.
Results: After matching, 108 patients were included and followed for 15– 38 months. Compared to the ACDF group, the EA-ACDF group had less intraoperative bleeding volume, less drainage volume, and shorter postoperative hospital stays (P < 0.05). At 7 days and 3 months after the surgery, the visual analog scale (VAS), Japanese Orthopedic Association score (JOA), and neck disability index (NDI) improved more significantly in the EA-ACDF group (P < 0.05). Regarding imaging, intervertebral height index (IHI), C2-7 cervical lordosis (C2-7 CL), and C2-7 range of motion (C2-7 ROM) exhibited no statistical differences between the two groups (P > 0.05). The complication rates between the EA-ACDF (3.7%) and ACDF (14.8%) groups demonstrated statistical differences (P = 0.046).
Conclusion: Both EA-ACDF and conventional ACDF for single-segment CSM provide satisfactory clinical efficacy. The EA-ACDF procedure provides a clearer surgical field, causes less trauma, allows faster recovery, and has the potential to reduce the risk of complications.
Keywords: cervical spondylotic myelopathy, anterior cervical discectomy and fusion, spinal endoscopy, complications, propensity score matching
Orthopedics of TCM Senior Department, the Sixth Medical Center of PLA General Hospital, Beijing, People’ s Republic of China
*These authors contributed equally to this work
Correspondence: Yu Ding, Orthopedics of TCM Senior Department, the Sixth Medical Center of PLA General Hospital, Beijing, People’ s Republic of China, Email cosmos_dingyu@163.com
Purpose: Endoscopy-assisted anterior cervical discectomy and fusion (EA-ACDF), which integrates the advantages of conventional ACDF and spinal endoscopy, is an innovative technique for treating cervical spondylotic myelopathy (CSM). We compared the clinical efficacy of EA-ACDF and ACDF for treating patients with single-segment CSM.
Methods: One-hundred and thirty-six CSM patients were retrospectively included from January 2021 to September 2023, of whom 61 underwent EA-ACDF and 75 underwent ACDF. Propensity score matching (PSM) was conducted to adjust for imbalances in covariates between groups. Then, clinical and imaging outcomes, perioperative data, and complications were compared.
Results: After matching, 108 patients were included and followed for 15– 38 months. Compared to the ACDF group, the EA-ACDF group had less intraoperative bleeding volume, less drainage volume, and shorter postoperative hospital stays (P < 0.05). At 7 days and 3 months after the surgery, the visual analog scale (VAS), Japanese Orthopedic Association score (JOA), and neck disability index (NDI) improved more significantly in the EA-ACDF group (P < 0.05). Regarding imaging, intervertebral height index (IHI), C2-7 cervical lordosis (C2-7 CL), and C2-7 range of motion (C2-7 ROM) exhibited no statistical differences between the two groups (P > 0.05). The complication rates between the EA-ACDF (3.7%) and ACDF (14.8%) groups demonstrated statistical differences (P = 0.046).
Conclusion: Both EA-ACDF and conventional ACDF for single-segment CSM provide satisfactory clinical efficacy. The EA-ACDF procedure provides a clearer surgical field, causes less trauma, allows faster recovery, and has the potential to reduce the risk of complications.
Keywords: cervical spondylotic myelopathy, anterior cervical discectomy and fusion, spinal endoscopy, complications, propensity score matching