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已发表论文
中国女性围产期体重变化与盆腔器官脱垂及体重变化之间的关联
Authors Wang G, Zhou L, Yu R, Wang X, Cui H
Received 23 July 2025
Accepted for publication 19 November 2025
Published 24 December 2025 Volume 2025:17 Pages 5623—5630
DOI https://doi.org/10.2147/IJWH.S550259
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Matteo Frigerio
Guan Wang,1 Li Zhou,2 Rao Yu,3 Xiaoqin Wang,3 Hongyan Cui1
1Department of Obstetrics,Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, People’s Republic of China; 2Department of Gynecology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, People’s Republic of China; 3Department of Obstetrics and Gynecology, First People’s Hospital of Wanzhou District, Chongqing, People’s Republic of China
Correspondence: Xiaoqin Wang, Department of Obstetrics and Gynecology, First People’s Hospital of Wanzhou District, No. 388, Tiancheng East Road, Zhoujiaba Street, Wanzhou District, Chongqing, 404000, People’s Republic of China, Tel +86 023 58376705, Email wangxiaoqin0627@163.com Hongyan Cui, Department of Obstetrics,Tianjin Central Hospital of Gynecology Obstetrics, No. 156, the Nankai Third Road, Tianjin, 300100, People’s Republic of China, Tel +86 022 58287057, Email 18920196039/Cuihy@126.com
Background: Pelvic organ prolapse (POP) is a global problem that severely affects a woman’s quality of life. This study aimed to investigate the association between weight change during pregnancy and post-pregnancy POP.
Methods: This study retrospectively enrolled 640 participants from Tianjin Central Hospital of Gynecology Obstetrics (institution 1, n = 363 cases) in northern China and First People’s Hospital of Wanzhou District, Chongqing (institution 2, n = 277 cases) in southwestern China. The participants were grouped into POP-Q I–II (n = 288), POP-Q III–IV (n = 132), and non-POP groups (control group, n = 220). Pre-pregnancy body mass index (BMI), weight gain during pregnancy, and weight retention at 6 months postpartum were compared among the three groups after eliminating confounding factors.
Results: No statistically significant differences were detected in the pre-pregnancy BMI in the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared to the control group (P > 0.05). Significant statistical differences (P < 0.05) were observed in weight gain during pregnancy (≥ 14 kg) in the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared with the control group. Significant statistical differences (P < 0.05) were observed in weight retention (≥ 5 kg) at 6 months postpartum among the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared to the control group.
Conclusion: Weight change during the perinatal period is the risk factor of postpartum POP. Specifically, a pre-pregnancy BMI < 23 kg/m2 did not increase the risk of POP, whereas gestational weight gain ≥ 14 kg and weight retention ≥ 5 kg at 6 months postpartum significantly increased the risk of postpartum POP. Weight management programs during and after pregnancy may help reduce the risk of POP.
Keywords: perinatal period, pre-pregnancy BMI, weight gain during pregnancy, weight retention postpartum, pelvic organ prolapse
1Department of Obstetrics,Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, People’s Republic of China; 2Department of Gynecology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, People’s Republic of China; 3Department of Obstetrics and Gynecology, First People’s Hospital of Wanzhou District, Chongqing, People’s Republic of China
Correspondence: Xiaoqin Wang, Department of Obstetrics and Gynecology, First People’s Hospital of Wanzhou District, No. 388, Tiancheng East Road, Zhoujiaba Street, Wanzhou District, Chongqing, 404000, People’s Republic of China, Tel +86 023 58376705, Email wangxiaoqin0627@163.com Hongyan Cui, Department of Obstetrics,Tianjin Central Hospital of Gynecology Obstetrics, No. 156, the Nankai Third Road, Tianjin, 300100, People’s Republic of China, Tel +86 022 58287057, Email 18920196039/Cuihy@126.com
Background: Pelvic organ prolapse (POP) is a global problem that severely affects a woman’s quality of life. This study aimed to investigate the association between weight change during pregnancy and post-pregnancy POP.
Methods: This study retrospectively enrolled 640 participants from Tianjin Central Hospital of Gynecology Obstetrics (institution 1, n = 363 cases) in northern China and First People’s Hospital of Wanzhou District, Chongqing (institution 2, n = 277 cases) in southwestern China. The participants were grouped into POP-Q I–II (n = 288), POP-Q III–IV (n = 132), and non-POP groups (control group, n = 220). Pre-pregnancy body mass index (BMI), weight gain during pregnancy, and weight retention at 6 months postpartum were compared among the three groups after eliminating confounding factors.
Results: No statistically significant differences were detected in the pre-pregnancy BMI in the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared to the control group (P > 0.05). Significant statistical differences (P < 0.05) were observed in weight gain during pregnancy (≥ 14 kg) in the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared with the control group. Significant statistical differences (P < 0.05) were observed in weight retention (≥ 5 kg) at 6 months postpartum among the POP-Q I–IV, POP-Q I–II, and POP-Q III–IV groups compared to the control group.
Conclusion: Weight change during the perinatal period is the risk factor of postpartum POP. Specifically, a pre-pregnancy BMI < 23 kg/m2 did not increase the risk of POP, whereas gestational weight gain ≥ 14 kg and weight retention ≥ 5 kg at 6 months postpartum significantly increased the risk of postpartum POP. Weight management programs during and after pregnancy may help reduce the risk of POP.
Keywords: perinatal period, pre-pregnancy BMI, weight gain during pregnancy, weight retention postpartum, pelvic organ prolapse