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已发表论文
颈椎骨肿瘤的影像学评估：综述
Authors Sun M, Meng X, Wu M, Wang Z
Received 30 August 2025
Accepted for publication 8 December 2025
Published 25 December 2025 Volume 2025:18 Pages 7785—7798
DOI https://doi.org/10.2147/IJGM.S564210
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Ching-Hsien Chen
Man Sun, Xianghong Meng, MengShan Wu, Zhi Wang
Radiology Department, Tianjin Hospital, Tianjin, People’s Republic of China
Correspondence: Zhi Wang, Email wangzhi13820256789@163.com
Abstract: The cervical spine, a critical junction between the head and torso, is a rare but significant site for both primary and metastatic tumors. While primary tumors of the cervical spine are uncommon, certain types, such as chordomas and giant cell tumors, are particularly notable for their potential to affect this region. Metastatic lesions, although more frequent, present unique diagnostic and therapeutic challenges due to the complex anatomy of the cervical spine. Imaging is indispensable for the evaluation of cervical spine tumors, serving as the foundation for diagnosis, treatment planning, and monitoring therapeutic outcomes. Radiography, CT and MRI are the primary modalities used to assess tumor morphology, extent and relationship to surrounding structures. However, imaging alone may not always yield a definitive diagnosis, as some tumors lack distinctive features. Nevertheless, a combination of clinical presentation, epidemiological factors, and imaging findings often enables radiologists and clinicians to narrow the differential diagnosis and guide further management. Precise imaging interpretation is essential to prevent devastating clinical consequences resulting from diagnostic error, such as irreversible neurological damage, avoidable death, and significant long-term disability. This review provides a comprehensive overview of tumors that can involve the cervical spine, emphasizing their clinical and imaging characteristics. By highlighting key diagnostic features and discussing the latest advancements in imaging technology, aims to enable physicians in radiology, pathology, and clinical departments to gain a more comprehensive understanding of the imaging, pathological, and clinical characteristics of cervical spine tumors, thereby reducing misdiagnosis rates and alleviating the burden on patients.
Keywords: cervical tumors, cervical spine, spine, X-ray, CT, MRI
Radiology Department, Tianjin Hospital, Tianjin, People’s Republic of China
Correspondence: Zhi Wang, Email wangzhi13820256789@163.com
Abstract: The cervical spine, a critical junction between the head and torso, is a rare but significant site for both primary and metastatic tumors. While primary tumors of the cervical spine are uncommon, certain types, such as chordomas and giant cell tumors, are particularly notable for their potential to affect this region. Metastatic lesions, although more frequent, present unique diagnostic and therapeutic challenges due to the complex anatomy of the cervical spine. Imaging is indispensable for the evaluation of cervical spine tumors, serving as the foundation for diagnosis, treatment planning, and monitoring therapeutic outcomes. Radiography, CT and MRI are the primary modalities used to assess tumor morphology, extent and relationship to surrounding structures. However, imaging alone may not always yield a definitive diagnosis, as some tumors lack distinctive features. Nevertheless, a combination of clinical presentation, epidemiological factors, and imaging findings often enables radiologists and clinicians to narrow the differential diagnosis and guide further management. Precise imaging interpretation is essential to prevent devastating clinical consequences resulting from diagnostic error, such as irreversible neurological damage, avoidable death, and significant long-term disability. This review provides a comprehensive overview of tumors that can involve the cervical spine, emphasizing their clinical and imaging characteristics. By highlighting key diagnostic features and discussing the latest advancements in imaging technology, aims to enable physicians in radiology, pathology, and clinical departments to gain a more comprehensive understanding of the imaging, pathological, and clinical characteristics of cervical spine tumors, thereby reducing misdiagnosis rates and alleviating the burden on patients.
Keywords: cervical tumors, cervical spine, spine, X-ray, CT, MRI