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已发表论文
银屑病负担的全球趋势及未来预测：来自 2021 年全球疾病负担研究的见解
Authors Gu X , Wang X , Bin Y, Xue R, Zhu G
Received 5 August 2025
Accepted for publication 25 November 2025
Published 24 December 2025 Volume 2025:15 Pages 569—580
DOI https://doi.org/10.2147/PTT.S558419
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Mio Nakamura
Xiaoyu Gu,1,* Xinquan Wang,2,* Yang Bin,1 Ruzeng Xue,1 Guannan Zhu1
1Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Guannan Zhu, Dermatology Hospital, Southern Medical University, 2 Lujing Road, Guangzhou, Guangdong, 510000, People’s Republic of China, Email zhuguannan@smu.edu.cn Ruzeng Xue, Dermatology Hospital, Southern Medical University, 2 Lujing Road, Guangzhou, Guangdong, 510000, People’s Republic of China, Email xueruzeng@163.com
Background: Psoriasis is a common chronic inflammatory skin disorder, and the global burden of psoriasis has not been fully disclosed.
Methods: We extracted prevalence, incidence and disability-adjusted life years (DALYs) for psoriasis from 1990 to 2021 in Global Burden of Disease (GBD) and predicted trends in the next 15 years though ARIMA model.
Results: Globally, age-standardized incidence rate (ASIR) of psoriasis increased from 57 cases/100,000 people (95% CI: 55.3~58.8) in 1990 to 62 cases/100,000 people (95% CI: 60.1~63.9) in 2021. Age-standardized prevalence rate (ASPR) and age-standardized disability-adjusted life year rate (ASDR) exhibited similar trends of increases. The global ASIR, ASPR, and ASDR for males were significantly higher than females. In 2021, ASIR peaked in the 55– 69 ages, while ASPR and ASDR reached peaks between the ages of 65– 74. Regionally, ASPR, ASIR, and ASDR in 2021 were highest in high Socio-demographic index (SDI) regions. The highest global regions and countries of ASPR, ASIR and ASDR were Western Europe and Germany, respectively. The East Asia region and Republic of Equatorial Guinea showed most significant growth in these psoriasis indicators since 1990. Furthermore, there was a significant increase in ASIR (8.06%), ASPR (8.14%), and ASDR (13.64%) of global psoriasis over the next 15 years.
Conclusions: Global burden of psoriasis is expected to continuously increase, and strengthening risk-factor management and prioritizing high-risk subgroups (males, elderly, high SDI regions and Western Europe, etc) will be essential for region-specific strategies and future healthcare planning.
Keywords: psoriasis, prevalence, incidence, disability-adjusted life years
1Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Guannan Zhu, Dermatology Hospital, Southern Medical University, 2 Lujing Road, Guangzhou, Guangdong, 510000, People’s Republic of China, Email zhuguannan@smu.edu.cn Ruzeng Xue, Dermatology Hospital, Southern Medical University, 2 Lujing Road, Guangzhou, Guangdong, 510000, People’s Republic of China, Email xueruzeng@163.com
Background: Psoriasis is a common chronic inflammatory skin disorder, and the global burden of psoriasis has not been fully disclosed.
Methods: We extracted prevalence, incidence and disability-adjusted life years (DALYs) for psoriasis from 1990 to 2021 in Global Burden of Disease (GBD) and predicted trends in the next 15 years though ARIMA model.
Results: Globally, age-standardized incidence rate (ASIR) of psoriasis increased from 57 cases/100,000 people (95% CI: 55.3~58.8) in 1990 to 62 cases/100,000 people (95% CI: 60.1~63.9) in 2021. Age-standardized prevalence rate (ASPR) and age-standardized disability-adjusted life year rate (ASDR) exhibited similar trends of increases. The global ASIR, ASPR, and ASDR for males were significantly higher than females. In 2021, ASIR peaked in the 55– 69 ages, while ASPR and ASDR reached peaks between the ages of 65– 74. Regionally, ASPR, ASIR, and ASDR in 2021 were highest in high Socio-demographic index (SDI) regions. The highest global regions and countries of ASPR, ASIR and ASDR were Western Europe and Germany, respectively. The East Asia region and Republic of Equatorial Guinea showed most significant growth in these psoriasis indicators since 1990. Furthermore, there was a significant increase in ASIR (8.06%), ASPR (8.14%), and ASDR (13.64%) of global psoriasis over the next 15 years.
Conclusions: Global burden of psoriasis is expected to continuously increase, and strengthening risk-factor management and prioritizing high-risk subgroups (males, elderly, high SDI regions and Western Europe, etc) will be essential for region-specific strategies and future healthcare planning.
Keywords: psoriasis, prevalence, incidence, disability-adjusted life years