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已发表论文
单纯 Ahmed 青光眼阀植入术与联合超声乳化术治疗中国原发性开角型青光眼的比较
Authors Fu L, Liu X, Ping Y, Zhuang X, Yao S, Yu S, Wang H, Yao S, Pan W
Received 26 June 2025
Accepted for publication 30 September 2025
Published 4 November 2025 Volume 2025:19 Pages 4067—4076
DOI https://doi.org/10.2147/OPTH.S549432
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Lin Fu,1 Xinyi Liu,1,2 Yijing Ping,1 Xiaoyu Zhuang,1 Shumeng Yao,1 Shuhan Yu,1 Hexiang Wang,1 Shenglu Yao,1 Weihua Pan1,3
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Ophthalmology, People’s Hospital of Yichun, Yichun, Jiangxi, People’s Republic of China; 3Department of Glaucoma, Hangzhou Aier Eye Hopital, Hangzhou, Zhejiang, People’s Republic of China
Correspondence: Weihua Pan, Email pan_weihua@163.com
Introduction: To compare the surgical outcomes of Ahmed glaucoma valve (AGV) implantation and combined AGVwith phacoemulsification (Phaco-AGV) in Chinese patients with primary open-angle glaucoma (POAG).
Methods: A total of 43 eyes followed up for 2 years were enrolled. The primary outcome was the success rate. The success rate was defined as an IOP of 5– 21 mmHg (success rate 1) or 5– 18 mmHg (success rate 2), and an IOP reduction of more than 20% with (qualified) or without (complete) glaucoma medications. The secondary outcomes included IOP, glaucoma medications, and complications.
Results: Eighteen eyes underwent AGV and 25 eyes underwent phaco-AGV. There were no differences in the preoperative IOP (25.7 ± 10.7 mmHg vs 26.3 ± 6.2 mmHg, P< 0.05) and medications (2.1 ± 1.4 vs 1.6 ± 0.8, P< 0.05) between the two groups. The complete success rate 1 in the Phaco-AGV group was higher than that in the AGV group at the 2-year (60.0% vs 22.2%, P< 0.05) follow-up. The qualified and complete success rates 2 in the Phaco-AGV group were both higher than those in the AGV group at the 2-year follow-up (all P < 0.05). Patients in the Phaco-AGV group showed significantly lower postoperative IOP at 3 months (P< 0.05), used fewer glaucoma medications at month-3, month-6 and year-2 visits, experienced less encapsulated blebs than those in the AGV group (P< 0.05).
Conclusion: The surgical outcomes of phaco-AGV showed higher success rates and fewer complications than those of AGV in this 2-year study.
Keywords: Ahmed glaucoma valve, phacoemulsification, tube, glaucoma device drainage, Chinese Primary Open Angle Glaucoma
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Ophthalmology, People’s Hospital of Yichun, Yichun, Jiangxi, People’s Republic of China; 3Department of Glaucoma, Hangzhou Aier Eye Hopital, Hangzhou, Zhejiang, People’s Republic of China
Correspondence: Weihua Pan, Email pan_weihua@163.com
Introduction: To compare the surgical outcomes of Ahmed glaucoma valve (AGV) implantation and combined AGVwith phacoemulsification (Phaco-AGV) in Chinese patients with primary open-angle glaucoma (POAG).
Methods: A total of 43 eyes followed up for 2 years were enrolled. The primary outcome was the success rate. The success rate was defined as an IOP of 5– 21 mmHg (success rate 1) or 5– 18 mmHg (success rate 2), and an IOP reduction of more than 20% with (qualified) or without (complete) glaucoma medications. The secondary outcomes included IOP, glaucoma medications, and complications.
Results: Eighteen eyes underwent AGV and 25 eyes underwent phaco-AGV. There were no differences in the preoperative IOP (25.7 ± 10.7 mmHg vs 26.3 ± 6.2 mmHg, P< 0.05) and medications (2.1 ± 1.4 vs 1.6 ± 0.8, P< 0.05) between the two groups. The complete success rate 1 in the Phaco-AGV group was higher than that in the AGV group at the 2-year (60.0% vs 22.2%, P< 0.05) follow-up. The qualified and complete success rates 2 in the Phaco-AGV group were both higher than those in the AGV group at the 2-year follow-up (all P < 0.05). Patients in the Phaco-AGV group showed significantly lower postoperative IOP at 3 months (P< 0.05), used fewer glaucoma medications at month-3, month-6 and year-2 visits, experienced less encapsulated blebs than those in the AGV group (P< 0.05).
Conclusion: The surgical outcomes of phaco-AGV showed higher success rates and fewer complications than those of AGV in this 2-year study.
Keywords: Ahmed glaucoma valve, phacoemulsification, tube, glaucoma device drainage, Chinese Primary Open Angle Glaucoma