109451
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
年轻成人结直肠腺瘤性息肉的代谢行为危险因素
Authors Zheng Q, Li Z , Hu J, Chu Y, Shi X
Received 1 August 2025
Accepted for publication 10 October 2025
Published 27 October 2025 Volume 2025:18 Pages 251—257
DOI https://doi.org/10.2147/CEG.S553734
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Vipul Yagnik
Quan Zheng, Zaizai Li, Jiangtian Hu, Yukun Chu, Xiaolong Shi
Department of Gastroenterology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan, People’s Republic of China
Correspondence: Zaizai Li, Department of Gastroenterology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan, People’s Republic of China, Email lizai0110@163.com
Objective: This study aimed to identify risk factors associated with colorectal adenomatous polyps in young adults (≤ 40 years) to support early prevention and screening strategies for colorectal cancer.
Methods: We conducted a study involving 805 young patients who underwent colonoscopy at the Endoscopy Center of The Fifth Affiliated Hospital of Zhengzhou University, China, from September 2023 to January 2025. Among them, 288 patients had at least one pathologically confirmed adenomatous polyp (cases), and 517 patients with no detected polyps served as controls. Data on demographics, lifestyle habits (smoking, alcohol use), metabolic parameters, and hematological indices were collected and analyzed.
Results: Several factors were significantly associated with an increased risk of adenomatous polyps, including male sex, hypertension, diabetes, smoking, alcohol consumption, elevated body mass index, and reduced high-density lipoprotein cholesterol (HDL-C). Multivariate analysis further identified hypertension, alcohol use, and higher red blood cell count as independent risk factors. Conversely, female sex and higher HDL-C levels were found to be protective.
Conclusion: The development of colorectal adenomatous polyps in young adults is strongly linked to modifiable risk factors such as hypertension and alcohol consumption, as well as elevated red blood cell counts. These findings highlight the importance of addressing cardiovascular and metabolic health, along with lifestyle modifications, in early screening and prevention programs for high-risk young individuals.
Keywords: adenomatous, colorectal polyps, young adults, risk factors, colorectal cancer
Department of Gastroenterology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan, People’s Republic of China
Correspondence: Zaizai Li, Department of Gastroenterology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan, People’s Republic of China, Email lizai0110@163.com
Objective: This study aimed to identify risk factors associated with colorectal adenomatous polyps in young adults (≤ 40 years) to support early prevention and screening strategies for colorectal cancer.
Methods: We conducted a study involving 805 young patients who underwent colonoscopy at the Endoscopy Center of The Fifth Affiliated Hospital of Zhengzhou University, China, from September 2023 to January 2025. Among them, 288 patients had at least one pathologically confirmed adenomatous polyp (cases), and 517 patients with no detected polyps served as controls. Data on demographics, lifestyle habits (smoking, alcohol use), metabolic parameters, and hematological indices were collected and analyzed.
Results: Several factors were significantly associated with an increased risk of adenomatous polyps, including male sex, hypertension, diabetes, smoking, alcohol consumption, elevated body mass index, and reduced high-density lipoprotein cholesterol (HDL-C). Multivariate analysis further identified hypertension, alcohol use, and higher red blood cell count as independent risk factors. Conversely, female sex and higher HDL-C levels were found to be protective.
Conclusion: The development of colorectal adenomatous polyps in young adults is strongly linked to modifiable risk factors such as hypertension and alcohol consumption, as well as elevated red blood cell counts. These findings highlight the importance of addressing cardiovascular and metabolic health, along with lifestyle modifications, in early screening and prevention programs for high-risk young individuals.
Keywords: adenomatous, colorectal polyps, young adults, risk factors, colorectal cancer