已发表论文

羊水栓塞并发肝破裂:一例报告

 

Authors Xu Y , Zhang Y, Zheng J, Chen C, Xu X, Yan J

Received 24 June 2025

Accepted for publication 17 October 2025

Published 29 October 2025 Volume 2025:17 Pages 3929—3935

DOI https://doi.org/10.2147/IJWH.S549171

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Elie Al-Chaer

Yanhong Xu,1– 4,* Yulong Zhang,1– 4,* Jiaying Zheng,1– 4 ChunXia Chen,1,5 Xia Xu,1– 4 Jianying Yan1– 4 

1College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 2Fujian Clinical Research Center for Maternal-Fetal Medicine, Fuzhou, Fujian, People’s Republic of China; 3Laboratory of Maternal-Fetal Medicine, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, People’s Republic of China; 4National Key Obstetric Clinical Specialty Construction Institution, Fuzhou, Fujian, People’s Republic of China; 5Imaging Department for Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Jianying Yan, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University Fujian Maternity and Child Health Hospital, No. 18 Daoshan Road, Gulou District, Fuzhou, Fujian, People’s Republic of China, Email yanjy2019@fjmu.edu.cn

Background: Amniotic fluid embolism (AFE) is a rare but highly fatal complication during delivery. It occurs when amniotic fluid suddenly enters the maternal circulation, causing acute multi-organ failure. Prompt recognition and management are crucial for improving survival rates.
Case Presentation: We reported a 37-year-old woman at 39 weeks gestation who developed AFE during labor induction. The patient presented with sudden cyanosis, dyspnea, and restlessness, followed by cardiac arrest during emergency cesarean section. Postoperative refractory postpartum hemorrhage (RPPH) necessitated multiple interventions, including hysterectomy and vascular embolization. Subsequent laparotomy revealed a subcapsular hematoma with linear tear in the left hepatic lobe, which was successfully repaired. The patient required massive transfusion and intensive care but eventually stabilized.
Conclusion: This case involved a life-threatening AFE complicated by cardiac arrest, RPPH, and traumatic liver rupture. The patient was successfully treated through multidisciplinary collaboration. It highlights three key aspects of critical maternal care: rapid recognition, damage control, and systemic resuscitation.

Keywords: amniotic fluid embolism, hepatic rupture, disseminated intravascular coagulation, post-partum hemorrhage, subcapsular hematoma