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已发表论文
偏头痛女性患者感知压力、心理韧性、心理健康与疼痛之间的关系：一项病例对照研究
Authors Arlud S , Tong N, Xie N, Gao S, He N
Received 12 December 2024
Accepted for publication 31 March 2025
Published 13 October 2025 Volume 2025:18 Pages 5399—5408
DOI https://doi.org/10.2147/JPR.S487780
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Rune Häckert Christensen
Sarnai Arlud,1,2 Narengerel Tong,3 Nabucha Xie,3 Sargai Gao,1 Nagongbilige He4
1Department of Psychosomatic Medicine, Inner Mongolia International Mongolian Hospital, Hohhot, People’s Republic of China; 2Department of Psychosomatic Medicine, Ordos Mongolian Medicine Hospital, Ordos, People’s Republic of China; 3School of Mongolian Medicine, Inner Mongolia Medical University, Hohhot, People’s Republic of China; 4Research Institution of Psychosomatic Medicine, Inner Mongolia Autonomous Region Traditional Chinese and Mongolian Medicine Research Institute, Hohhot, People’s Republic of China
Correspondence: Sarnai Arlud, Department of Psychosomatic Medicine, Inner Mongolia International Mongolian Hospital, 83# Da Xue Dong street, Saihan District, Hohhot, Inner Mongolia, 010065, People’s Republic of China, Tel +86 15661057622, Email sarnai@gjmyemail.gjmyy.cn
Purpose: The protective role of resilience against migraine remains understudied, and the present study examined the role of resilience in the relationship between perceived stress, mental health, and pain in female migraineurs and healthy women.
Patients and methods: In this case-control study, 125 female migraineurs and 121 healthy female controls were included. The Perceived Stress Scale (PSS-13), Connor-Davidson Resilience Scale (CD-RISC-10), and SF12 health-related quality-of-life questionnaire were used for assessments mental (MCS) and physical (PCS) health condition. Correlation and mediation analyses were performed.
Results: Female migraineurs exhibited significantly higher perceived stress, lower resilience, and worse quality of life, including pain and MCS (all p < 0.05). Resilience partially mediated the relationship between perceived stress and MCS in healthy women, but not in migraineurs. Mental health fully mediated the relationship between perceived stress and pain in migraineurs, while in healthy women, both resilience and MCS sequentially mediated this relationship.
Conclusion: Resilience does not protect against the mental health impact of perceived stress in female migraineurs but has a partial protective effect in healthy women. Mental health mediates the impact of perceived stress on pain among migraineurs. These findings underscore the need for targeted stress management and resilience-building interventions in clinical practice for better outcomes in women with migraines.
Keywords: female migraines, perceived stress, psychiatric disorders, resilience
1Department of Psychosomatic Medicine, Inner Mongolia International Mongolian Hospital, Hohhot, People’s Republic of China; 2Department of Psychosomatic Medicine, Ordos Mongolian Medicine Hospital, Ordos, People’s Republic of China; 3School of Mongolian Medicine, Inner Mongolia Medical University, Hohhot, People’s Republic of China; 4Research Institution of Psychosomatic Medicine, Inner Mongolia Autonomous Region Traditional Chinese and Mongolian Medicine Research Institute, Hohhot, People’s Republic of China
Correspondence: Sarnai Arlud, Department of Psychosomatic Medicine, Inner Mongolia International Mongolian Hospital, 83# Da Xue Dong street, Saihan District, Hohhot, Inner Mongolia, 010065, People’s Republic of China, Tel +86 15661057622, Email sarnai@gjmyemail.gjmyy.cn
Purpose: The protective role of resilience against migraine remains understudied, and the present study examined the role of resilience in the relationship between perceived stress, mental health, and pain in female migraineurs and healthy women.
Patients and methods: In this case-control study, 125 female migraineurs and 121 healthy female controls were included. The Perceived Stress Scale (PSS-13), Connor-Davidson Resilience Scale (CD-RISC-10), and SF12 health-related quality-of-life questionnaire were used for assessments mental (MCS) and physical (PCS) health condition. Correlation and mediation analyses were performed.
Results: Female migraineurs exhibited significantly higher perceived stress, lower resilience, and worse quality of life, including pain and MCS (all p < 0.05). Resilience partially mediated the relationship between perceived stress and MCS in healthy women, but not in migraineurs. Mental health fully mediated the relationship between perceived stress and pain in migraineurs, while in healthy women, both resilience and MCS sequentially mediated this relationship.
Conclusion: Resilience does not protect against the mental health impact of perceived stress in female migraineurs but has a partial protective effect in healthy women. Mental health mediates the impact of perceived stress on pain among migraineurs. These findings underscore the need for targeted stress management and resilience-building interventions in clinical practice for better outcomes in women with migraines.
Keywords: female migraines, perceived stress, psychiatric disorders, resilience