109568
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
褪黑素紊乱对帕金森病的影响：机制与临床表现综述
Authors Shen Y , He C , Wang Y, Zhang Y, Liu Z, Chen X, Wang S, Bai Y
Received 23 May 2025
Accepted for publication 30 July 2025
Published 18 October 2025 Volume 2025:21 Pages 2335—2355
DOI https://doi.org/10.2147/NDT.S536997
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Taro Kishi
Yiwei Shen,1,* Cong He,1,* Yulin Wang,1 Yu Zhang,1 Zhengnan Liu,1 Xia Chen,1 Shun Wang,1,* Yan Bai2,*
1The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2Institute of Acupuncture and Moxibustion, Heilongjiang Academy of Traditional Chinese Medicine, Harbin, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Shun Wang, The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China, Email hljwang@aliyun.com Yan Bai, Institute of Acupuncture and Moxibustion, Heilongjiang Academy of Traditional Chinese Medicine, Harbin, People’s Republic of China, Email 1447003128@qq.com
Abstract: Melatonin is a vital hormone that is important for antioxidant activity, neuroprotection, and biological rhythm control. Melatonin anomalies may have a high correlation with the onset and development of Parkinson’s disease, according to recent studies. A common neurodegenerative illness that severely lowers a patient’s quality of life, Parkinson’s disease is typified by non-motor symptoms and aberrant movement. A recent study found that abnormal melatonin levels may have a detrimental effect on patients’ motor function and cognitive ability, potentially exacerbating Parkinson’s disease symptoms. To completely comprehend the clinical symptoms linked to Parkinson’s disease and potential therapy options, further study is necessary to determine the exact role of melatonin in this condition. This article will investigate the relationship between melatonin and Parkinson’s disease, how it contributes to the illness’s progression, and the clinical symptoms that are linked with it in order to provide new perspectives and resources for more research and treatment strategies.
Keywords: melatonin, Parkinson’s disease, mechanism, clinical manifestations, neuroprotection
1The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2Institute of Acupuncture and Moxibustion, Heilongjiang Academy of Traditional Chinese Medicine, Harbin, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Shun Wang, The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China, Email hljwang@aliyun.com Yan Bai, Institute of Acupuncture and Moxibustion, Heilongjiang Academy of Traditional Chinese Medicine, Harbin, People’s Republic of China, Email 1447003128@qq.com
Abstract: Melatonin is a vital hormone that is important for antioxidant activity, neuroprotection, and biological rhythm control. Melatonin anomalies may have a high correlation with the onset and development of Parkinson’s disease, according to recent studies. A common neurodegenerative illness that severely lowers a patient’s quality of life, Parkinson’s disease is typified by non-motor symptoms and aberrant movement. A recent study found that abnormal melatonin levels may have a detrimental effect on patients’ motor function and cognitive ability, potentially exacerbating Parkinson’s disease symptoms. To completely comprehend the clinical symptoms linked to Parkinson’s disease and potential therapy options, further study is necessary to determine the exact role of melatonin in this condition. This article will investigate the relationship between melatonin and Parkinson’s disease, how it contributes to the illness’s progression, and the clinical symptoms that are linked with it in order to provide new perspectives and resources for more research and treatment strategies.
Keywords: melatonin, Parkinson’s disease, mechanism, clinical manifestations, neuroprotection