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已发表论文
肛瘘术后复发的多因素分析：一项回顾性研究
Received 27 April 2025
Accepted for publication 4 September 2025
Published 22 September 2025 Volume 2025:18 Pages 6015—6024
DOI https://doi.org/10.2147/JMDH.S537028
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Charles V Pollack
Fang Fang,1 Luping Wen2
1Department of Anorectal Surgery, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai, 519015, People’s Republic of China; 2Department of Coloproctology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221005, People’s Republic of China
Correspondence: Luping Wen, Department of Coloproctology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai Western Road, Quanshan Area, Xuzhou, 221005, People’s Republic of China, Email wenluping@xzhmu.edu.cn
Background: The aim of this study is to investigate the main factors that influence the recurrence of anal fistulas in patients with perianal abscesses following incision and drainage treatment.
Methods: A retrospective case-control study was performed according to the STROBE guidelines for patients with perianal abscesses who underwent surgical treatment at Guangdong Provincial Hospital of Chinese Medicine in Zhuhai and at the Affiliated Hospital of Xuzhou Medical University in Lasso between June 2021 and June 2023. Lasso and multivariate logistic regression analyses were performed to further determine the recurrence of perianal abscesses.
Results: A total of 435 patients were included in the study, with a median follow-up period of 25 months (range 18– 40 months) after receiving treatment for perianal abscesses. Of these patients, 27 were in the anal fistula group and 408 were in the cured group. The results of the multivariate logistic regression analysis showed that a history of abscesses, enteritis, intraoperative pus cavity residue, standardized dressing changes after discharge, the surgeon’s specialty, preoperative ultrasound or MRI examination, Parks classification and Wexner score were independently influential factors in the formation of anal fistulas after perianal abscess surgery (P < 0.05).
Conclusion: A history of abscesses and enteritis, Parks classification, and intraoperative pus cavity residue are high-risk factors for anal fistula recurrence. Standardized dressing changes after discharge, a preoperative ultrasound or MRI scan, and a postoperative assessment of anal function (Wexner score) are important for protecting anal sphincter function and improving the prognosis of perianal abscesses.
Keywords: perianal abscess, recurrence, anal fistula, risk factor
1Department of Anorectal Surgery, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai, 519015, People’s Republic of China; 2Department of Coloproctology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221005, People’s Republic of China
Correspondence: Luping Wen, Department of Coloproctology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai Western Road, Quanshan Area, Xuzhou, 221005, People’s Republic of China, Email wenluping@xzhmu.edu.cn
Background: The aim of this study is to investigate the main factors that influence the recurrence of anal fistulas in patients with perianal abscesses following incision and drainage treatment.
Methods: A retrospective case-control study was performed according to the STROBE guidelines for patients with perianal abscesses who underwent surgical treatment at Guangdong Provincial Hospital of Chinese Medicine in Zhuhai and at the Affiliated Hospital of Xuzhou Medical University in Lasso between June 2021 and June 2023. Lasso and multivariate logistic regression analyses were performed to further determine the recurrence of perianal abscesses.
Results: A total of 435 patients were included in the study, with a median follow-up period of 25 months (range 18– 40 months) after receiving treatment for perianal abscesses. Of these patients, 27 were in the anal fistula group and 408 were in the cured group. The results of the multivariate logistic regression analysis showed that a history of abscesses, enteritis, intraoperative pus cavity residue, standardized dressing changes after discharge, the surgeon’s specialty, preoperative ultrasound or MRI examination, Parks classification and Wexner score were independently influential factors in the formation of anal fistulas after perianal abscess surgery (P < 0.05).
Conclusion: A history of abscesses and enteritis, Parks classification, and intraoperative pus cavity residue are high-risk factors for anal fistula recurrence. Standardized dressing changes after discharge, a preoperative ultrasound or MRI scan, and a postoperative assessment of anal function (Wexner score) are important for protecting anal sphincter function and improving the prognosis of perianal abscesses.
Keywords: perianal abscess, recurrence, anal fistula, risk factor