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Authors Zhang L, Wang Q, Wang L, Shen J, Zhang Q, Sun C
Received 20 May 2016
Accepted for publication 7 July 2016
Published 22 February 2017 Volume 2017:12 Pages 431—436
DOI https://doi.org/10.2147/CIA.S113240
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Akshita Wason
Peer reviewer comments 3
Editor who approved publication: Professor Zhi-Ying Wu
Objective: Percutaneous vertebroplasty (PVP) is a surgical procedure that has been
widely used to treat patients suffering from osteoporotic vertebral compression
fractures (OVCFs). The procedure involves injection of bone cement into a
fractured vertebra. In this study, we investigated whether the distribution of
the cement in the vertebral body is related to the occurrence of recompression
after surgery.
Patients and methods: A total of 172 patients diagnosed with OVCF, from
January 2008 to June 2013, were retrospectively reviewed. Fifty of these
patients experienced recompression after surgery during the follow-up period
(recompression group), and 122 patients had no recompression observed during
the follow-up period (control group). Statistical analysis was performed to
compare clinical and operative parameters between these two groups.
Results: Differences were found in bone cement distribution
between the recompression group and control group (P =0.001).
Patients with bone cement distributed around both upper and lower endplates had
a significantly less incidence of recompression (4/50 patients), when compared
to other patterns of cement distribution (eg, below upper endplate, above lower
endplate, and in the middle of vertebral body). The logistic multiple
regression analysis also indicated that patients with bone cement distributed
around both the upper and lower endplates had a lower risk of recompression
when compared to patients with bone cement distributed in the middle of
vertebral body (odds ratio =0.223, P =0.003).
Conclusion: We herein suggest that the control of bone cement
distribution during surgery provides beneficial effects on reducing the risks
of recompression after PVP treatment in patients with OVCF.
Keywords: elderly, OVCF, PVP, bone cement