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大疱性类天疱疮和落叶型天疱疮共存：一项病例报告
Authors Yuan J , Yao X, Liu L, Zhang J
Received 22 August 2024
Accepted for publication 15 November 2024
Published 28 November 2024 Volume 2024:17 Pages 2725—2731
DOI https://doi.org/10.2147/CCID.S486976
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Anne-Claire Fougerousse
摘要：落叶型天疱疮（PF）和大疱性类天疱疮（BP）是两种不同的自身免疫性大疱性皮肤病，分别由靶向黏附分子、桥粒和表皮-基底膜区半桥粒结构蛋白的自身抗体介导。PF与BP的共存非常罕见。我们报道了一名72岁男性患者，该患者同时具有PF和BP的临床和组织学特征。经过免疫球蛋白（10克/天，共3天）、静脉注射磷酸地塞米松钠（5毫克/天，共10天）、口服曲安奈德（30毫克/天，共10天）、以及盐酸米诺环素（20毫克/天，共10天）的治疗后，患者症状显著改善。这一罕见病例强调了对PF和BP共存的准确诊断和有效治疗策略的重要性。