已发表论文

微小 RNA 在肺癌中潜在的临床应用和前景

 

Authors Gao Y, Gao F, Ma JL, Sun WZ, Song LP

Published Date June 2014 Volume 2014:7 Pages 901—906

DOI http://dx.doi.org/10.2147/OTT.S62227

Received 11 February 2014, Accepted 6 April 2014, Published 4 June 2014

Abstract: Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.

Keywords: microRNA, lung cancer, biomarker, chemotherapy, radiotherapy